Syphilitic gumma

Carvalho, Marcio F. de; Carvalho, Adriana F. de; Zyngier, Felix R.

doi:10.1016/s0035-9203(96)90316-8

Cited by 2 publications

(3 citation statements)

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“…Approximately one-third of untreated syphilis results in tertiary syphilis, and the progression to this stage ranges from several months to 35 years after infection 2 3. The most common clinical forms of tertiary syphilis are neurosyphilis, cardiovascular syphilis (syphilitic aortitis) and gummatous syphilis 4.…”

Section: Descriptionmentioning

confidence: 99%

“…Syphilitic gummas account for approximately 16% of tertiary syphilis manifestations and are rarely contagious 3. They present as rounded or oval subcutaneous nodules measuring 2–10 cm and constitutional symptoms are usually absent 2. The size of the gummas is highly variable, but severe lesions, also known as rupioid lesions, have been described in malnourished patients 4…”

Section: Descriptionmentioning

confidence: 99%

“…3 They present as rounded or oval subcutaneous nodules measuring 2-10 cm and constitutional symptoms are usually absent. 2 The size of the gummas is highly variable, but severe lesions, also known as rupioid lesions, have been described in malnourished patients. 4 Cases of cranial, facial, hard palate and other syphilitic gummas have been reported in literature.…”

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confidence: 99%

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Perineal syphilitic gumma: tertiary syphilis in a developed country

2022

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Section: Descriptionmentioning

confidence: 99%

Section: Descriptionmentioning

confidence: 99%

Section: Images In…mentioning

confidence: 99%

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Perineal syphilitic gumma: tertiary syphilis in a developed country

2022

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Syphilitic myositis: a case-based review

et al. 2011

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To present the clinical and pathological findings in patients presenting with myositis caused by syphilis. The literature is reviewed, and pathophysiologic factors discussed. A 49-year-old Caucasian heterosexual male with a known history of stable human immunodeficiency virus (HIV) and hepatitis C (HCV) co-infection, developed progressive muscle weakness over 10 weeks. He discontinued his medications; however, he had on-going muscle symptoms. A muscle biopsy was performed, consistent with mild myositis. While on prednisone therapy, he developed panuveitis and vertigo. CSF studies were positive for syphilis (Treponema pallidum). He was started on appropriate antibiotic therapy with complete clinical resolution. This patient presented with myositis and panuveitis as a manifestation of acute onset of syphilis. Syphilis is an uncommon cause of myositis. In patients with HIV and/or HCV, the disease itself and side effects of the medications must be considered. As patients with HIV may have co-infections, syphilis must be considered, especially when unresponsive to traditional management.

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Syphilitic gumma

Cited by 2 publications

References 3 publications

Perineal syphilitic gumma: tertiary syphilis in a developed country

Perineal syphilitic gumma: tertiary syphilis in a developed country

Syphilitic myositis: a case-based review

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