Syringic Acid: Structural Elucidation and Co-Crystallization

Thipparaboina, Rajesh; Mittapalli, Sudhir; Thatikonda, Sowjanya; Nangia, Ashwini; Naidu, V.G.M.; Shastri, Nalini R.

doi:10.1021/acs.cgd.6b00750

Cited by 39 publications

(26 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…From a single crystal, it was found that syringic acid received from the supplier as well syringic acid recrystallized from 2-butanone, acetonitrile and dimethylformamide crystalized in monoclinic C system with cell parameters of a = 26.64 Å, b = 4.14 Å, c = 15.84 Å, β = 96.30°, which are comparable to those published in CCDC database (CCDC number: 1450484) [60]. Fig.…”

Section: Solid Phase Studiessupporting

confidence: 74%

See 1 more Smart Citation

Solvent and temperature effects on the solubility of syringic, vanillic or veratric acids: Experimental, modeling and solid phase studies

Vilas-Boas

Vieira

Brandão

et al. 2019

Journal of Molecular Liquids

View full text Add to dashboard Cite

The solubility of syringic acid, vanillic acid and veratric acid was measured in pure water and eleven organic solvents (methanol, ethanol, 1-propanol, 2-propanol, 2-butanone, ethyl acetate, acetonitrile, dimethylformamide, 1,2-propanediol, 1,3-propanediol and 1,3-butanediol), at 298.2 K and 313.2 K. Besides the solubility data, the melting temperatures and enthalpies of the solutes were determined by differential scanning calorimetry, while powder and single X-ray diffraction were used to resolve the solute solid structure, before and after the solubility studies. For modeling purposes, the NRTL-SAC model, also combined with the Reference Solvent Approach (RSA), and the Abraham solvation model were applied to describe the solid-liquid equilibria of the binary systems. A set of solvents was used to estimate the model parameters and afterwards, solubility predictions were carried out for binary systems not included in the correlation step. Better results were obtained using the Abraham solvation model with average relative deviations (ARD) of 15% for the correlation set and 26% for the predictions, which are more satisfactory than the results found with the NRTL-SAC model (33% for the correlation and 59% for the predictions) or the NRTL-SAC model combined with RSA (30% for the correlation and 59% for the predictions).

show abstract

Section: Solid Phase Studiessupporting

confidence: 74%

“…The melting temperatures and enthalpies found in literature [16,21,23,[57][58][59][60] along with the values measured in this work by DSC, and by the visual method, are summarized in Table 3. Exemplificative thermograms for the DSC measurements are shown in Fig.…”

Section: Melting Propertiesmentioning

confidence: 79%

Solvent and temperature effects on the solubility of syringic, vanillic or veratric acids: Experimental, modeling and solid phase studies

Vilas-Boas

Vieira

Brandão

et al. 2019

Journal of Molecular Liquids

View full text Add to dashboard Cite

show abstract

“…For SyA‐Co 2 Fe, two peaks at 710.88 and 724.53 eV can be assigned to Fe 2p 3/2 and Fe 2p 1/2 , respectively . The binding energy of 710.25, 724.4 and a small satellite peak at 717.6 eV implied the presence of Fe 2+ species . There are still two relatively weak peaks at 713.26 and 731.18 eV, which are assigned to Fe 3+ ion .…”

Section: Methodsmentioning

confidence: 96%

“…For the as‐prepared MOFs, the broad absorption peaks at 3227–3363 cm −1 in the ligand disappeared, suggesting the carboxylate groups and aryloxy binds to the Fe or Co ions. The peaks at 2837 and 617 cm −1 correspond to the C−H vibration of the methoxy groups, whereas the peak at 1110 cm −1 is attributed to the C−O−C bond, confirming the methoxy group is still in the benzene ring . Moreover, the peaks at 1384 and 1665 cm −1 correspond to the ν as (−COO−) and ν s (−COO−) coordination bonds between the SyA and the metal centers .…”

Section: Methodsmentioning

confidence: 98%

Rational Design of a N,S Co‐Doped Supermicroporous CoFe–Organic Framework Platform for Water Oxidation

et al. 2020

View full text Add to dashboard Cite

It remains ac hallenge to rational design of an ew metal-organic framework (MOF)a sh ighly efficient direct electrocatalysts for the oxygen evolution reaction(OER). Herein, we developed as imple and effective method to explore an ew pillaredlayered MOF with syringic acid as ap romising OER electrocatalyst. The isostructuralm ono-, heterobimetallic MOF and N,S codoped MOF by mixing thiourea were quicklys ynthesized in a high yield under solvothermal condition. Moreover,t he optimized N,S co-doped MOF exhibits the lowest overpotential of 254 mV at 10 mA cm À2 on ag lass carbon electrode andas mall Ta fel slope of 50 mV dec À1 ,e specially,t his catalysta lso possesses long-term electrochemical durability for at least 16 h. According to the characterization, the incorporationo fNa nd S atoms into this heterobimetallic CoFe-based MOF could modify its pore structure,t une the electronic structure, accordingly,i mprove the mass and electron transportation,a nd facilitate the formation of active species, as ac onsequence, the improveda ctivity of this new N,S co-doped MOF for OER should be mainly be ascribed to higher electrochemical activation toward the actives peciesv ia in situ surface modification during the OER process.Metal-organic frameworks (MOFs), especially,p illared-layered MOFs, are rising star materials in the field of materials science because of their ultrafinep orosity,r ich active metal-sites and tunable structures, which have attracted enormousi nterest and have aw idespread application in catalysis, energy conversion technologies, and environmentally friendly technologies. [1][2][3][4][5][6][7][8][9][10][11][12][13] In particular,M OFs have been employed as high active electrocatalysts to improvet he sluggish reactionk inetics of water oxidation[ i.e.,t he oxygen evolution reaction (OER)] as one of the determine steps and the key processes in water splitting and metal-air batteries. [5][6][7][8][9][10][11][12][13] However,m ost of direct MOFs as electrocatalysts have poor long-term electrochemical durability in reaction media (strong acid or strongb ase), limiting their practical application in the field of water splitting since the long-term stability and high activity are equally importantf or catalysts. [14][15][16][17][18][19] Besides, it is criticalt hat improving MOF conductivity to enhancet heir intrinsic catalytic activity because of their low electronic conductivity and poor mass permeability.O ne effective strategy is to fabricate their derivatives through high temperature pyrolysis or chemical conversions, [20][21][22][23][24][25][26][27][28][29][30][31][32][33] such as metal oxides or hydroxides, [24][25][26] carbonbased derivatives, [27][28][29][30] and composite materials. [31][32][33] Although these derivatives exhibit improved electrocatalytic performance compared with the pristine MOFs precursors, during the pyrolysis, the intrinsics tructure of MOFs has been destroyed, simultaneously,t hese expensive organic ligands have been decomposed, severely hampering their practically largesca...

show abstract

“…The current status of their availability is summarized in Table 6 [29,38,39]. The chemical structures of some of the common compounds, isolated from these plants and their biological activities tested so far, have been depicted in (19) Anthelmintic [165][166] α-Bulnesene (20) Inhibit platelet-activating factor, anti-inflammatory [167][168] Quinine (21) Antimalaria [169] Kaempferol (22) Antioxidant & antimicrobial [170][171] Protocatechuic acid (23) Anticancer, antidiabetic, anti-inflammatory, antioxidant & anti aging, cardioprotective , antimicrobial, antifibrotic activity, antihepatitic activity, neuroprotective, antihyperlipidemia, protection against reproductive toxicity [172][173][174][175][176][177][178][179][180][181][182][183][184][185][186] Syringic acid (24) Reduce diabetic cataract by inhibiting aldose reductase antioxidant, antiproliferative, antiendotoxic, antimicrobial, anti-inflammatory, and anticancer, anti-angiogenic, anti-glycating, antihyperglycaemic, neuroprotective, and memoryenhancing properties [187][188][189] Peiminine (25) Anticancer anti-allergic & anti inflammatory [190][191][192]…”

Section: Botanical Description and Ayurvedic Usesmentioning

confidence: 99%

Phytochemical, Botanical and Biological Paradigm of Astavarga Plants- The Ayurvedic Rejuvenators

Misra¹

2018

JONAM

View full text Add to dashboard Cite

Astavarga is nature's most extravagant group of flowering plants found in Himalayan region. As the name Astavarga indicates, it contains eight medicinal plants belonging to Zingiberaceae, Orchidaceae and Liliaceae family viz, Kakoli, Kshirakakoli, Meda, Mahameda, Jeevak, Risbhaka, Riddhi and Vridddhi. As per Ayurveda this group of medicinal plants is classified as Rasayana (Rejuvenation) and is important constituents of preparations like Chyawanprasha rasayan, Ashtavarga churna, Brimhanigutika and Vajikaraghrita, etc. Astavarga plants are mostly used to treat sexual disorders, physical weakness, body pain, strengthen the immune system and as an overall tonic. The plants under this group have been the subject of limited biochemical phytochemical and biological activities investigations. Taking into consideration the therapeutic significance of Astavarga plants as described in the ancient Ayurvedic system of medicine, the detailed phytochemical and pharmacological studies appear imperative to scientifically validate the ancient claims. Thus, the present review article provides detailed information on the Ayurvedic uses, habit and habitats, botanical descriptions, chemical constituents and biological activities reported for this important group of plants. The chemical structures of the isolated compounds from these plants and their reported biological activities in the literature have also been included.The information provided in the present review may stimulate the researchers to explore their phytochemical and pharmacological properties which have not yet been attempted, comprehensively. It will generate the interest on "reverse pharmacology" approach to validate the knowledge that has been known from ancient times.

show abstract

Syringic Acid: Structural Elucidation and Co-Crystallization

Cited by 39 publications

References 33 publications

Solvent and temperature effects on the solubility of syringic, vanillic or veratric acids: Experimental, modeling and solid phase studies

Solvent and temperature effects on the solubility of syringic, vanillic or veratric acids: Experimental, modeling and solid phase studies

Rational Design of a N,S Co‐Doped Supermicroporous CoFe–Organic Framework Platform for Water Oxidation

Phytochemical, Botanical and Biological Paradigm of Astavarga Plants- The Ayurvedic Rejuvenators

Contact Info

Product

Resources

About