Systematic Evaluation and Meta-analysis of Banxia Baizhu Tianma Decoction and Zexie Decoction Combined with Conventional Western Medicine in the Treatment of Hypertension

Wu, Qianyan; Zhang, Ying; Zhou, Xu; Zhang, Qingyuan; Yu, Ling; Chen, Hongfu; Ao, Meiying

doi:10.37766/inplasy2021.8.0068

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“…The incidence of adverse reactions was 4.41 and 2.94%, respectively. Wu and Sun (40) reported four kinds of adverse reactions: nausea and vomiting, fever, local skin allergy, and systemic reaction; the incidence of adverse events was 18.50%. Guo (21) reported the recurrence of some cases during treatment and retching and fatigue during follow-up, all of which occurred in the control group.…”

Section: Adverse Eventsmentioning

confidence: 99%

Acupuncture and related therapies for tension-type headache: a systematic review and network meta-analysis

Wang

Jia

et al. 2023

Front. Neurol.

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BackgroundTension-type headache (TTH) is one of the most common primary headaches. Several studies have confirmed the efficacy of acupuncture therapies for TTH, but it is uncertain which treatment is most effective.ObjectiveThis study aimed to compare the effectiveness and safety of different acupuncture therapies for TTH using Bayesian Network Meta-analysis to provide new ideas for treating TTH.MethodsNine databases were searched for randomized controlled trials (RCTs) about different acupuncture therapies for TTH up to December 1, 2022. The outcome indicators analyzed in our study were total effective rate, visual analog scale (VAS), headache frequency, and safety. Pairwise meta-analysis and risk of bias assessment were performed using Review Manager 5.4. Stata 15.0 generated a network evidence plot and detected publication bias. Finally, a Bayesian network meta-analysis of the data was used by RStudio.ResultsThe screening process resulted in 30 RCTs that met the inclusion criteria, including 2,722 patients. Most studies failed to report details of trials and were therefore assessed as unclear risks. Two studies were considered high risk because they did not report on all pre-specified outcome indicators or had incomplete data on outcome indicators. The NMA results showed that for total effective rate, bloodletting therapy had the most considerable SUCRA value (0.93156136), for VAS, head acupuncture combined with Western medicine ranked first (SUCRA = 0.89523571), and acupuncture combined with herbal medicine was the most effective in improving headache frequency (p > 0.05).ConclusionAcupuncture can be used as one of the complementary or alternative therapies for TTH; bloodletting therapy better improves the overall symptoms of TTH, head acupuncture combined with Western medicine is more effective in reducing VAS scores, and acupuncture combined with herbal medicine seems to reduce headache frequency, but the difference is not statistically significant. Overall, acupuncture for TTH is effective with mild side effects, but future high-quality studies are still necessary.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, PROSPERO [CRD42022368749].

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Section: Adverse Eventsmentioning

confidence: 99%

Acupuncture and related therapies for tension-type headache: a systematic review and network meta-analysis

Wang

Jia

et al. 2023

Front. Neurol.

View full text Add to dashboard Cite

show abstract

Systematic Evaluation and Meta-analysis of Banxia Baizhu Tianma Decoction and Zexie Decoction Combined with Conventional Western Medicine in the Treatment of Hypertension

Abstract: To systematically evaluate the efficacy of Banxia Baizhu Tianma Decoction and Zexie Decoction combined with conventional western medicine in the treatment of hypertension, and to provide a basis for the decision-making of clinical medication for INPLASY 1

Cited by 1 publication

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Acupuncture and related therapies for tension-type headache: a systematic review and network meta-analysis

Acupuncture and related therapies for tension-type headache: a systematic review and network meta-analysis

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