Systematic review and meta-analysis of local recurrence rates of head and neck cutaneous melanomas after wide local excision, Mohs micrographic surgery, or staged excision

Lentigo Maligna of the head and neck: A retrospective study assessing surgical excision margins in a South African population

“…SE offers a superior alternative to conventional WLE with complete peripheral margin evaluation resulting in lower recurrence rates. 3 , 11 , 12 , 13 , 14 …”

“…Recurrence rates for LM of the head and neck treated with SE are reported in other studies to be as low as 1.8%. 12 …”

“…Previous studies confirmed that SE with rushed permanent sections is superior in obtaining clearance and reduced recurrence rates when compared to conventional WLE since it allows for complete control of the peripheral excision margins. 3 , 11 , 12 , 13 , 14 Recurrence rates for LM after SE have been reported as 1.8% to 4%. 11 , 12 …”

Commentary on “Recurrence Rate for Melanoma Excised by Mohs Micrographic Surgery Without Immunostaining”

“…A recent metaanalysis showed only slightly lower cure rates with staged excision compared with MMS without special stains. 9 In an early study in 1997, Zitelli and colleagues 10 reported a 5-year cure rate for MMS for melanoma without special stains. He found a 99.5% cure rate for in situ melanoma and between a 0.5% and 1.4% recurrence rate for invasive melanoma, the former rate (0.5%) for adjacent recurrence and the latter (1.4%) for within 5 cm of the scar.…”

“…A recent meta-analysis showed only slightly lower cure rates with staged excision compared with MMS without special stains. 9…”