Systematic Review, Meta-analysis and Meta-regression of Epidemiological Studies for Cardiovascular Risk Factors in Turkey: Smoking Data

Özer, Necla; Kılıçkap, Mustafa; Tokgözoğlu, Lâle; Göksülük, Hüseyin; Karaaslan, Doruk; Kayıkçıoğlu, Meral; Yılmaz, Mehmet; Barçın, Cem; Abacı, Adnan; Şahin, Mahmut

doi:10.5543/tkda.2018.85349

Cited by 11 publications

(14 citation statements)

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“…The smoking history of the patients in the control group was 34.6%, similar to the smoking rate in Turkey; 9 whereas, 69.2% of the HIV (+) patients had a history of smoking. Data on BMI in HIV-infected patients were examined and various studies have found that the prevalence of overweight or obesity ranged from 10.7% to 50%.…”

Section: 8supporting

confidence: 55%

The Value of Carotid Intima-Media Thickness in the Detection of Atherosclerosis in HIV (+) Patients Subclinical Atherosclerosis in HIV (+)

Ozdemir

Özdemir

Birlik

et al. 2021

J Coll Physicians Surg Pak

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Section: 8supporting

confidence: 55%

The Value of Carotid Intima-Media Thickness in the Detection of Atherosclerosis in HIV (+) Patients Subclinical Atherosclerosis in HIV (+)

Ozdemir

Özdemir

Birlik

et al. 2021

J Coll Physicians Surg Pak

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“…A limitation of this study was the fact that smoking was not considered as an exclusion factor since one‐third of the Turkish population >15 years are smokers (Ozer et al, ). Smoking impacts both cholinergic systems (Wessler, Kilbinger, Bittinger, Unger, & Kirkpatrick, ; Wessler & Kirkpatrick, ) and IL‐17 immunity (Qiu et al, ).…”

Section: Discussionmentioning

confidence: 99%

Cholinergic signalling mechanisms and early implant healing phases in healthy versus generalized aggressive periodontitis patients: A prospective, case–control study

Meriç

Buduneli

Kanmaz

et al. 2019

J Clinic Periodontology

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Aims Periodontal diseases negatively affect implant osseointegration. Perturbations in non‐neuronal cholinergic signalling mechanisms are associated with periodontitis; however, their role in generalized aggressive periodontitis (GAgP) is unknown. The aim of this prospective case–control study was to determine the relationship between non‐neuronal cholinergic signalling mechanisms, secreted Ly‐6/uPAR‐related protein‐1 (SLURP‐1), interleukin‐17 (IL‐17) family cytokines and healing of dental implants in health and GAgP. Material and Methods Thirteen GAgP patients and seven periodontally healthy individuals (PH) were recruited. Peri‐implant crevicular fluid (PICF) was obtained at baseline and 1 month post‐placement. Acetylcholine (ACh) levels and cholinesterase activity were determined biochemically. SLURP‐1, IL‐17A and IL‐17E levels were determined by ELISA. Marginal bone loss (MBL) at 1 and 6 months post‐placement was determined radiographically. Results The concentration of ACh, cholinesterase activity and IL‐17A levels was elevated in PICF of patients with GAgP compared to PH individuals at baseline and 1 month post‐placement. The concentration of ACh and cholinesterase activity levels in PICF correlated with levels of IL‐17A and MBL around implants 1 month post‐placement in patients with GAgP. Conclusions Non‐neuronal cholinergic mechanisms may play a role in the aetiopathogenesis of GAgP and may directly or indirectly, through modulation of IL‐17A, influence early implant osseointegration and potential long‐term implant survival.

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“…The most prevalent risk factors in Turkey are hypertension, tobacco use, obesity, hypercholesterolemia, and diabetes [ 3 , [12] , [13] , [14] , [15] , [16] ]. Except for smoking, all of these risk factors are significantly more common in women than in men.…”

Section: Major Cardiovascular Risk Factorsmentioning

confidence: 99%

“…Among these Turkish Adults Risk Factors Study (TARF) − the earliest and longest epidemiological study was a comprehensive cohort study that evaluated CVD and its risk factors in Turkey from 1992 to 2016 [ 7 , 17 ]. More recently, Turkish Society of Cardiology (TSC) conducted meta-analyses enrolling epidemiologic studies with low bias and high representativeness of the country population distribution using data from the past 15 years [12] , [13] , [14] , [15] , [16] . These meta-analyses revealed an overall prevalence of hypertension 31.2%, smoking 30.3%, hypercholesterolemia 29.1%, diabetes 14.6%, obesity 28.5%, and metabolic syndrome 43.3%.…”

Section: Major Cardiovascular Risk Factorsmentioning

confidence: 99%

The landscape of preventive cardiology in Turkey: Challenges and successes

Tokgözoğlu

Kayıkçıoğlu

Ekinci

2021

American Journal of Preventive Cardiology

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Turkey, like many countries, is facing a growing burden of non-communicable disease (NCD)s and is among the countries with high cardiovascular mortality in Europe. Moreover, Turkey currently has the highest rate of premature cardiovascular disease (CVD) in Europe. During the last decades, Turkey made fundamental reforms in the health system to improve the treatment of risk factors to prevent CVD. The most outstanding success was in the area of tobacco control (13.4% decrease in smoking prevalence) and decreasing the salt consumption of the population (from 18 to 9.9 g/day) leading to a significant decrease in CVD mortality from 45% to 36.8% of all deaths. However, obesity and diabetes are increasing rapidly as a result of urbanization, low physical activity and unhealthy eating and the new generation is starting to take up smoking. The increase in cardiometabolic risk factors and aging of the population are expected to increase the number of CVD deaths. All CVD risk factors except smoking are significantly more prevalent in women. In addition, rare disease is a country specific problem with a significant contribution to the high rates of premature CVD in Turkey. Despite major improvements in management in acute coronary syndromes, sustained achievement in guideline recommended goals is suboptimal. In patients with a previous cardiovascular event smoking rate is 25.5%, 80.9% of these patients are overweight (BMI ≥25 kg/m 2 ), 30% obese (BMI ≥30 kg/m 2 ), and LDL‐cholesterol targets of 70 mg/dL are attained in only 18%. Herein, we scrutinize the achievements and challenges of Turkey in establishing a ‘National Heart Health Policy’ aiming to decrease the burden of CVD and its risk factors.

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Systematic Review, Meta-analysis and Meta-regression of Epidemiological Studies for Cardiovascular Risk Factors in Turkey: Smoking Data

Cited by 11 publications

References 0 publications

The Value of Carotid Intima-Media Thickness in the Detection of Atherosclerosis in HIV (+) Patients Subclinical Atherosclerosis in HIV (+)

The Value of Carotid Intima-Media Thickness in the Detection of Atherosclerosis in HIV (+) Patients Subclinical Atherosclerosis in HIV (+)

Cholinergic signalling mechanisms and early implant healing phases in healthy versus generalized aggressive periodontitis patients: A prospective, case–control study

The landscape of preventive cardiology in Turkey: Challenges and successes

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