Systematic review of mesotherapy: a novel avenue for the treatment of hair loss

Gupta, Aditya K.; Polla Ravi, Shruthi; Wang, Tong; Talukder, Mesbah; Starace, Michela; Piraccini, Bianca Maria

doi:10.1080/09546634.2023.2245084

Cited by 7 publications

(5 citation statements)

References 43 publications

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“…According to Tang et al [ 11 ] and Gupta et al [ 12 ], there are five particular approaches for mesotherapy injection to prevent musculoskeletal strain caused by doing many injections in one place, with gauges 28-30 and 4 mm long, or with mesogen lasting 10-30 minutes. These five procedures differ in needle depth and/or angle of injection, which are as follows: (1) The intra-epidermal technique (depth: 1 mm) involves injecting multiple small amounts of the mesotherapy solution into the epidermis, often in a grid-like pattern 1 cm apart, covering the entire treatment area; each injection is applied with light pressure, causing minimal pain and no bleeding, making this technique suitable for patients with a low pain tolerance threshold.…”

Section: Reviewmentioning

confidence: 99%

“…(5) The microperfusion approach includes injecting the same mesotherapy fluid over 10 minutes. The sleeping and point-by-point techniques are the most commonly used for mesotherapy hair loss treatment [ 11 , 12 ].…”

Section: Reviewmentioning

confidence: 99%

“…However, in order to alleviate patient discomfort, several needleless procedures have been documented that may remove skin reactions while maintaining the same level of medicine penetration. This includes the use of low-power ultrasound (20-25 kHz), which may increase skin permeability by generating microscopic gas cavities, and iontophoresis, which improves transdermal medicine delivery by applying an electric current (0.5 mA/cm 2 ) [ 12 ].…”

Section: Reviewmentioning

confidence: 99%

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Mesotherapy as a Promising Alternative to Minoxidil for Androgenetic Alopecia: A Systematic Review

Aledani,

Kaur,

Kasapoglu

et al. 2024

Cureus

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Patterned hair loss (PHL) is a severe hair condition that affects both sexes. Mesotherapy is a treatment that involves microinjecting medications and/or vitamins into the middle layer of the skin. Mesotherapy reduces systemic adverse effects by delivering drugs directly to the hair follicle, increasing local bioavailability while lowering systemic exposure. Local side effects and reactions may develop due to mesotherapy. This study systematically evaluated the safety and efficacy of mesotherapy to minoxidil 5%, as well as addressing its limitations, dosing, and technique, with the intent of providing valuable trials and insights for clinicians and patients considering mesotherapy for improved androgenetic alopecia (AGA) outcomes. The literature search carried out by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria yielded 11 relevant studies from an initial pool of 18 articles. These studies covered various aspects of the role of mesotherapy and minoxidil in AGA, including techniques, complications, limitations, and outcomes. In conclusion, available trials and research on mesotherapy and minoxidil demonstrated excellent statistical significance and a high patient satisfaction rate, with the exception of two publications that took into account certain uncommon adverse effects of mesotherapy. However, recent research suggests that a mesotherapy method for alopecia with a low risk of side effects is effective.

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Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

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Mesotherapy as a Promising Alternative to Minoxidil for Androgenetic Alopecia: A Systematic Review

Aledani,

Kaur,

Kasapoglu

et al. 2024

Cureus

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“…It has been a popular choice for people looking for efficient and customized solutions because of its capacity to administer tailored therapies with little intrusiveness. The incorporation of the zygomaticotemporal block into platelet-rich plasma (PRP) therapy is an example of how the medical community is dedicated to improving mesotherapy methods so that patients can receive the most complete and advantageous care [16][17][18]. Since there is currently no evidence to support combining these blocks with other mesotherapy procedures, the purpose of this study was to evaluate the efficacy of zygomaticotemporal blocks in addition to supratrochlear and supraorbital blocks for mesotherapy in the temporal area.…”

Section: Introductionmentioning

confidence: 99%

Comparison of the Efficacy of Two Different Local Anesthesia Techniques for Mesotherapy in Temporal Region Alopecia

Nagaja,

John,

Kumar

et al. 2024

Cureus

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During the procedure, a mean VAS of 1 and 3 was observed in groups I and II, respectively, during the procedure (p-value 0.023). A mean VAS of 3 and 5 was observed in groups I and II, respectively, after three hours (p-value 0.000). This shows a significant difference in the pain experienced by the subjects between the groups. ConclusionThis study proves that the zygomaticotemporal nerve, used along with supratrochlear and supraorbital nerve blocks, is better at producing analgesia and reducing pain.

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“…Mesotherapy, involving the intradermal infusion of a mixture of factors, has demonstrated improvements in hair growth [90,104,105].…”

mentioning

confidence: 99%

Regenerative Cosmetics: Skin Tissue Engineering for Anti-Aging, Repair, and Hair Restoration

Pleguezuelos- Beltrán,

Herráiz-Gil,

Martínez-Moreno

et al. 2024

Preprint

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The quest for youthful, healthy skin and full, vibrant hair has long been a driving force in the dermocosmetics field. However, traditional approaches often struggle to address the underlying causes of aging, damage, and hair loss. Regenerative cosmetics, powered by skin tissue engineering, offer a transformative alternative. This review explores the emerging field of using engineered skin tissues for cosmetic purposes, focusing specifically on their potential for anti-aging, repair, and hair restoration applications. We discuss how these technologies aim to rejuvenate aging skin by promoting collagen production, reducing wrinkles, and improving overall skin function. Additionally, the use of engineered skin for wound healing and scar reduction is examined, highlighting their potential to improve the appearance and functionality of damaged skin. Finally, we advance the exciting prospects of utilizing skin tissue engineering techniques to regenerate hair follicles, potentially offering solutions for hair loss and promoting denser hair growth.

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Systematic review of mesotherapy: a novel avenue for the treatment of hair loss

Cited by 7 publications

References 43 publications

Mesotherapy as a Promising Alternative to Minoxidil for Androgenetic Alopecia: A Systematic Review

Mesotherapy as a Promising Alternative to Minoxidil for Androgenetic Alopecia: A Systematic Review

Comparison of the Efficacy of Two Different Local Anesthesia Techniques for Mesotherapy in Temporal Region Alopecia

Regenerative Cosmetics: Skin Tissue Engineering for Anti-Aging, Repair, and Hair Restoration

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