Systematic Review On Covid Vaccination In Children- Assessment Of Safety, Immunogenicity, Efficacy And Adverse Effects

Abstract

Introduction: The recent pandemic outbreak Covid-19 has led to substantial illness and ultimate mortality across the globe and childrenare highly are in the verge of being in a critical role as vectors in the transmission of SARS-CoV-2 in the community. There are quitea few studies which have observed that the vaccinated individuals who become infected again are on the side fewer side to transmit thevirus due to reduced viral load and the duration of virus shedding and as a result, transmission from vaccinated individual to householdcontacts is significantly lower. This systemic review was thus undertaken with the objective of analysing the literature that wereavailable on the safety, immunogenicity, efficacy and if any adverse effects of covid vaccination in children.Material and Methods: We conducted both a systematic review. This review was solely based on the predefined protocol and it wasconducted in concordance with PRISMA guidelines.Conclusion: The available data reports similar efficacy and safety in children as of adults. Therefore, more clinical trials are needed tobe conducted and published for evaluation of safety and if any long-term effects of Covid vaccines.