Systematic Review on Epstein-Barr Virus (EBV) DNA in Diagnosis of Nasopharyngeal Carcinoma in Asian Populations

Han, Bei‐Zhong; Xu, Xiangying; Zhang, Chunzhi; Wu, Jian-Juan; Han, Chun-Feng; Wang, Hui; Wang, Xuan; Wang, Guangshun; Yang, Shujuan; Xie, Yao

doi:10.7314/apjcp.2012.13.6.2577

Cited by 69 publications

(56 citation statements)

References 17 publications

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“…Reagents and experimental procedures were handled with high standards through the entire study. The specificity and sensitivity of VCA-IgA, EA-IgA, and EBV DNA observed were consistent with that previously reported (Luo et al, 2009;Han et al, 2012), validating the quality of our study. Our preliminary results identified EA-D p45-IgG as a promising new NPC biomarker.…”

Section: Discussionsupporting

confidence: 93%

EA-D p45-IgG as a Potential Biomarker for Nasopharyngeal Carcinoma Diagnosis

Chen

Luo²,

Zhang³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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Section: Discussionsupporting

confidence: 93%

EA-D p45-IgG as a Potential Biomarker for Nasopharyngeal Carcinoma Diagnosis

Chen

Luo²,

Zhang³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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“…NPC in the epidemic area is special because of its strong association with EBV and sustain higher levels of serum EBV-specific antibodies, especially isotypes of immunoglobulin A (IgA) (Henle et al, 1976;Ho et al, 1976;Han et al, 2012). Previous studies have shown that VcA-IgA and EA-IgA were particularly elevated in NPC patients (Sam et al, 1989;Low et al, 2000;Cheng et al, 2002;Tiwawech et al, 2003) and might provide information regarding the prognosis (Cai et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

ABO Blood Group, Epstein-Barr virus Infection and Prognosis of Patients with Non-metastatic Nasopharyngeal Carcinoma

Zhang¹,

Kang²,

Chen³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Asian Pac J Cancer Prev, 15 (17), [7459][7460][7461][7462][7463][7464][7465] Introduction Nasopharyngeal carcinoma (NPC) is a common head and neck malignant neoplasm, especially in southern China where the major pathological type of NPC is nonkeratinizing undifferentiated carcinoma (World Health Organization Type III) (Jemal et al., 2011;Huang et al., 2012). Several factors have been proved to enhance the risk of NPC, including Epstein-Barr virus (EBV), smoking, alcohol consumption, salt-preserved foods and family history of cancer, etc (Chien et al., 2001;Jia et al., 2010;Ji et al., 2011;Hashim et al., 2012).Extensive investigations have showed that the ABO blood group might be associated with risk to certain malignancies (Iodice et al., 2010;Gates et al., 2011;Joh et al., 2012;Wang et al., 2012;Zhang et al., 2014). A previous study suggested that blood type A or AB was associated with an increased risk of NPC and male patients with blood group A had higher rates of distant

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“…According to WHO classification system standard (2005), the pathological type of C666-1 is UCNT. Because of close relationship between UCNT and EBV (Klein et al, 1974;AnderssonAnvret et al, 1979;Wei et al, 1996;Han et al, 2012), the study data will be useful for clinical diagnosis and therapy of UCNT if C666-1 is used for further study.…”

Section: Discussionmentioning

confidence: 99%

Expression of the Pokemon Proto-oncogene in Nasopharyngeal Carcinoma Cell Lines and Tissues

Jiao

Liu²,

Tang³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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To study the differentiated expression of the proto-oncogene Pokemon in nasopharyngeal carcinoma (NPC) cell lines and tissues, mRNA and protein expression levels of CNE1, CNE2, CNE3 and C666-1 were detected separately by reverse transcription polymerase chain reaction (RT-PCR), real-time PCR and Western-blotting. The immortalized nasopharyngeal epithelial cell line NP69 was used as a control. The Pokemon protein expression level in biopsy specimens from chronic rhinitis patients and undifferentiated non keratinizing NPC patients was determined by Western-blotting and arranged from high to low: C666-1>CNE1>CNE2> CNE3>NP69. The Pokemon mRNA expression level was also arranged from high to low: CNE1>CNE2>NP69>C666-1>CNE3. Pokemon expression of NP69 and C666-1 obviously varied from mRNA to protein. The Pokemon protein level of NPC biopsy specimens was obviously higher than in chronic rhinitis. The data suggest that high Pokemon protein expression is closely associated with undifferentiated non-keratinizing NPC and may provide useful information for NPC molecular target therapy.

show abstract

Systematic Review on Epstein-Barr Virus (EBV) DNA in Diagnosis of Nasopharyngeal Carcinoma in Asian Populations

Cited by 69 publications

References 17 publications

EA-D p45-IgG as a Potential Biomarker for Nasopharyngeal Carcinoma Diagnosis

EA-D p45-IgG as a Potential Biomarker for Nasopharyngeal Carcinoma Diagnosis

ABO Blood Group, Epstein-Barr virus Infection and Prognosis of Patients with Non-metastatic Nasopharyngeal Carcinoma

Expression of the Pokemon Proto-oncogene in Nasopharyngeal Carcinoma Cell Lines and Tissues

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