Systemic lupus erythematosus: Pharmacological differences between women and men and among age groups and geographical regions

Valladales‐Restrepo, Luis Fernando; Constain-Mosquera, Camilo Alexander; Mesa-Ardila, María Clara; Machado‐Alba, Jorge Enrique

doi:10.1016/j.rcreu.2021.05.008

Cited by 2 publications

(1 citation statement)

References 25 publications

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“…The differences in the patterns of use of these medications can be due to multiple causes, including medical decisions that could be influenced by demographic, cultural and economic factors. Also to the academic training of the prescriber, adherence to management guidelines, and availability of the medications, their approved indications in each country and the characteristics of the patients, especially according to their comorbidities and disease severity (Valladales‐Restrepo, Constain‐Mosquera, et al., 2021; Valladales‐Restrepo et al., 2021).…”

Section: Discussionmentioning

confidence: 99%

Treatment patterns in fibromyalgia including the use of opioids

Valladales‐Restrepo

Oyuela-Gutiérrez

Alzate-García

et al. 2022

Musculoskeletal Care

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Objective: Opioids (except for tramadol) have not been shown to be effective in patients with fibromyalgia, but they can increase the risk of adverse drug reactions.The aim was to determine the treatment patterns of a group of patients with fibromyalgia and to identify the factors associated with the use of opioids in Colombia.Methods: This was a cross-sectional study of a group of patients with fibromyalgia from a pain clinic in Colombia. Sociodemographic, clinical and pharmacological variables were identified. Descriptive, bivariate, and multivariate analyses were performed.Results: A total of 559 patients were analysed, 88.6% of whom were women, and the mean age was 53.4 � 12.6 years. A total of 40.6% received nonpharmacological management, and the majority were treated with acetaminophen (96.1%) and pregabalin (62.8%). A total of 69.6% received opioids, the most common of which was hydrocodone (36.3%). The average morphine equivalent milligrammes was 36.9 � 91.2 (range: 2.3-750 mg), and 43.8% had intermediate/high doses. Being

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Section: Discussionmentioning

confidence: 99%

Treatment patterns in fibromyalgia including the use of opioids

Valladales‐Restrepo

Oyuela-Gutiérrez

Alzate-García

et al. 2022

Musculoskeletal Care

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Autoimmune Idiopathic Inflammatory Myopathies: Pharmacological Differences and Similarities by Type of Myositis and by Sociodemographic Variables

Valladales‐Restrepo

Delgado-Araujo

Aristizábal-Carmona

et al. 2022

International Journal of Rheumatology

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Objective. Autoimmune idiopathic inflammatory myopathies (IIMs) are a group of pathologies that are generally characterized by muscle weakness. Their treatment involves glucocorticoids and immunosuppressants. The aim was to identify differences and similarities in the pharmacological management of a group of patients with autoimmune IIMs according to the type of disease, sex, age group, and city of residence in Colombia from 2020 to 2021. Methods. This cross-sectional study identified medication prescription patterns for outpatient use in patients with autoimmune IIMs between 2020 and 2021 based on a population database of 8.5 million Colombians affiliated with the Colombian health system. Sociodemographic and pharmacological variables were considered. Results. A total of 671 patients with autoimmune IIMs were identified, with a median age of 57 years, and 70.9% were women. Overlap myositis was the most frequent disease (31.4%). A total of 91.5% of the patients received pharmacological treatment, mainly systemic glucocorticoids (78.5%), conventional disease-modifying antirheumatic drugs (DMARDs) (74.1%), immunosuppressants (9.1%), and biological DMARDs (3.7%). Pharmacological management predominated among patients with overlap myositis, those who lived in cities, and those affiliated with the contributory regime of the Colombian health system. Conventional DMARDs were prescribed mainly to women and to those older than 65 years. Conclusions. Patients with autoimmune IIMs are not treated homogeneously. The pattern of drug use varies according to the type of IIM, sex, age group, city, and health system regime affiliation.

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Systemic lupus erythematosus: Pharmacological differences between women and men and among age groups and geographical regions

Cited by 2 publications

References 25 publications

Treatment patterns in fibromyalgia including the use of opioids

Treatment patterns in fibromyalgia including the use of opioids

Autoimmune Idiopathic Inflammatory Myopathies: Pharmacological Differences and Similarities by Type of Myositis and by Sociodemographic Variables

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