Systemic sarcoidosis diagnosed by panniculitis mimicking olecranon bursitis associated to fingertip calcinosis cutis

Martín-Gorgojo, Alejandro; Alonso-Usero, V.; Gavrilova, Maria; Monteagudo-Castro, Carlos

doi:10.4103/0019-5154.143550

Cited by 8 publications

(6 citation statements)

References 5 publications

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“…In contrast, dystrophic calcinosis cutis has been rarely reported in patients with sarcoidosis. Some dystrophic calcinosis cutis lesions develop in cutaneous sarcoidosis lesions while others arise in non‐affected areas 9,10 …”

Section: Case Reportmentioning

confidence: 99%

“…Some dystrophic calcinosis cutis lesions develop in cutaneous sarcoidosis lesions while others arise in non‐affected areas. 9 , 10 …”

Section: Case Reportmentioning

confidence: 99%

“…Some dystrophic calcinosis cutis lesions develop in cutaneous sarcoidosis lesions while others arise in non-affected areas. 9,10 The pathophysiology of dystrophic calcinosis cutis remains controversial. It has been suggested that phosphate-binding protein released from necrotic cells induces phosphate deposition and consequent calcification at sites of trauma and inflammation.…”

Section: Case Reportmentioning

confidence: 99%

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Dystrophic calcinosis cutis in a patient with cutaneous sarcoidosis in remission

Yoshikawa

Akasaka

Nakano

et al. 2022

Skin Health and Disease

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A 65‐year‐old Japanese woman was referred to our department because of a 5‐month history of asymptomatic papules on the face. She was diagnosed with cutaneous sarcoidosis on the face 20 years ago. All of the lesions had completely disappeared with oral corticosteroids. Twenty years after the diagnosis of sarcoidosis, small papules developed in areas where the cutaneous sarcoidosis had been located. Physical examination revealed four yellow‐white papules on the face. Dermoscopy revealed a homogenous, round, and yellow‐white lesion. Serum levels of calcium and phosphorus were normal. Histopathology demonstrated calcium deposits in the dermis surrounded by inflammatory infiltrates without sarcoid granulomas. We made a diagnosis of calcinosis cutis. Basal cell carcinoma with calcinosis cutis, milia‐like calcinosis cutis, and subcutaneous calcified nodule should be differentiated. Calcinosis cutis can be classified into four subtypes based on pathogenesis: dystrophic, metastatic, idiopathic, and iatrogenic. Dystrophic calcinosis cutis is caused by local tissue damage or abnormalities. Whereas, metastatic calcinosis cutis is often associated with hypercalcaemia, hyperphosphatemia, or hyperparathyroidism. There are reported cases of metastatic calcinosis cutis associated with sarcoidosis because patients with sarcoidosis often present with hypercalcaemia. However, dystrophic calcinosis cutis associated with sarcoidosis has been rarely reported. In the present case, systemic treatment for sarcoidosis may have degraded sarcoid granulomas and yielded necrotic tissue and dermal fibrosis, which might have induced ectopic calcification. Thus, we thought the present case consisted of dystrophic calcinosis cutis that developed in areas with cutaneous sarcoidosis in remission.

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Section: Case Reportmentioning

confidence: 99%

“…Some dystrophic calcinosis cutis lesions develop in cutaneous sarcoidosis lesions while others arise in non‐affected areas. 9 , 10 …”

Section: Case Reportmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

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Dystrophic calcinosis cutis in a patient with cutaneous sarcoidosis in remission

Yoshikawa

Akasaka

Nakano

et al. 2022

Skin Health and Disease

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“…These lesions consist of tender bumps mostly on the shins and are most commonly seen in Caucasians. Calcinosis cutis, deposition of calcium salts within the skin, have also been noted in sarcoidosis and are often related to concomitant hypercalcemia [21].…”

Section: Organ Involvementmentioning

confidence: 99%

Sarcoidosis: The Organs Involved. A Primer for Primary Care Physicians

Rissmiller¹

2017

Int Arch Intern Med

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Sarcoidosis is a granulomatous disease of unknown etiology that can affect any organ. Management of sarcoidosis patients with the potential for multi-organ involvement can be complex and require the expertise of multiple specialties. The goal of this review is to discuss clinical, imaging and epidemiologic features of organ involvement in sarcoidosis, treatment strategies, and which patients are appropriate for referral to a clinic dedicated to the management of patients with sarcoidosis.

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“…One patient can have different lesions simultaneously. Cutaneous sarcoidosis is known as a great imitator in dermatology, or a "clinical chameleon" (13,14,15,16), because the lesions can have a wide range of clinical presentations.…”

mentioning

confidence: 99%

Cutaneous Sarcoidosis in a patient with left Hilar calcification of the lungs - A Case Report

Paravina

Ljubenović²,

Stanojević

et al. 2016

Serbian Journal of Dermatology and Venereology

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Sarcoidosis is an acquired idiopathic granulomatous disease, which is characterized by noncaseating epithelioid granulomas in organs and tissues. Most frequently it affects the lungs, liver, lymph nodes, skin, eyes and other organs. The cutaneous lesions appear in 20 -30% of patients with systemic manifestations, and in 25% of them they appear without systemic manifestations. Based on the histopathological characteristics, cutaneous lesions are divided into specific, characterized by cutaneous granuloma, and non-specific, which are not granulomatous. Moreover, they can be classified as typical and atypical. We are presenting a female patient with unilateral hilar calcification of the lungs, who exhibited plaque skin lesions typical for sarcoidosis, with a specific granulomatous histology and a favorable response to corticosteroid and antimalarial therapy.

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Systemic sarcoidosis diagnosed by panniculitis mimicking olecranon bursitis associated to fingertip calcinosis cutis

Cited by 8 publications

References 5 publications

Dystrophic calcinosis cutis in a patient with cutaneous sarcoidosis in remission

Dystrophic calcinosis cutis in a patient with cutaneous sarcoidosis in remission

Sarcoidosis: The Organs Involved. A Primer for Primary Care Physicians

Cutaneous Sarcoidosis in a patient with left Hilar calcification of the lungs - A Case Report

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