Systemic thrombolytic therapy in acute ischemic stroke — New experiences in spreading network of stroke units in Croatia

Clinical Policy: Use of Intravenous Tissue Plasminogen Activator for the Management of Acute Ischemic Stroke in the Emergency Department

“…25 Among other Class III studies, 33,36,37,41,44,50,55,56,58,61,66,[68][69][70][71][72][73][74][75][76][77] the prevalences of sICH associated with IV tPA administration within 4.5 hours ranged from 3% to 8% when based on the NINDS definition, whereas the prevalence was lower (2% to 6%) for those studies using an sICH definition requiring a change of 4 or more on the NIHSS. 39,53,54,57,60,[62][63][64][65]67,[78][79][80][81][82][83][84] …”