2020
DOI: 10.1101/2020.07.29.225425
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Systems and classical biology approaches unraveled role of olfactory receptors in progression of kidney fibrosis

Abstract: The olfactory receptors (ORs) which are mainly known as odor-sensors in the olfactory epithelium are distributed in several non-sensory tissues. Despite the specified role of some of these receptors in normal physiology of the kidney, little is known about their potential effect in renal disorders. In this study, using the holistic view of systems biology, it was determined that ORs are significantly changed during the progression of kidney fibrosis. For further validation, common differentially expressed ORs … Show more

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