Systolic and diastolic function in children with chronic renal failure

Abstract

The technique of CAPD has some advantages as a renal replacement therapy for preserving cardiac functions as compared with hemodialysis. However, it must be remembered that patients with hemodialysis have features that effects cardiac status, such as higher volume load and higher afterload (hypertension).

An Echocardiographic Assessment of Cardiac Functions and Structure in Children on Dialysis

“…[26][27][28][29] However, others could not confirm these findings and indicated that abnormalities in diastolic filling may occur early and before LVH and systolic dysfunction. [4,7] We did not find a significant correlation between LVMI and the E/A ratio, which was consistent with some reports in literature. [4,7,30] Because of the absence of a relation between LVMI and the E/A ratio, the diastolic dysfunction in our patients could not be fully attributed to an increased LVMI.…”

“…[4,[7][8][9] In adult patients on CAPD, LVH initially is of similar degree as in HD patients, but worsens with longer duration of treatment associated with systolic function and poor BP control. [10,11] In contrast to these findings, Atalay et al [4] demonstrated that IVST, PWT, and LVMI were significantly increased and LV volume/mass ratio was decreased in children on HD compared to those on CAPD, CRI, and control groups. [10,11] In the present study, statistically significant increases in IVST, PWT, and LVMI were observed in both HD and CAPD dialysis groups.…”

“…[4,25] These reports suggested that CAPD has some advantages as a renal replacement therapy for preserving cardiac functions compared to HD in children. In our study, the peak A velocity was increased and E/A ratio was decreased in both CAPD and HD groups when compared to controls whereas there was no change in the peak E velocity among four groups.…”

“…[6] Posterior wall thickness (PWT), interventricular septal thickness (IVST), left ventricular end-diastolic diameter (LVEDD), and left ventricular end-systolic diameter (LVESD) were measured and indexed for body surface area. [4] Left ventricular enddiastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), shortening fraction (SF), and ejection fraction (EF) were recorded. Left ventricular mass (LVM) was calculated by Devereux and Reichek's formula [6] and indexed for body surface area.…”

“…Left ventricular mass (LVM) was calculated by Devereux and Reichek's formula [6] and indexed for body surface area. [4] Mitral valve peak early diastolic flow velocity (E), peak late diastolic flow velocity (A), E/A ratio, and isovolemic relaxation time (IVRT) were estimated by transmitral Doppler echocardiography in the apical four chamber view. Isovolemic relaxation time was corrected for heart rate.…”