Systolic and diastolic function in patients with chronic heart failure at rest and during exercise

Local and general anaesthesia do not influence outcome of transfemoral aortic valve implantation

“…Rubin's multiple imputation procedure replaces each missing value with a set of plausible values, then analysed by using standard procedures for complete data and combining the results from these analyses, using the programme R (http://www.R-project.org/.) [18] and the package Hmisc (http://CRAN.Rproject.org/package=Hmisc) [19]. We planned to evaluate relationship between anaesthesia and in-hospital mortality according to patients' risk profile assessed by tertiles of Logistic EuroSCORE (the lowest risk group defined as a Log-EuroSCOREs b10.4%, the intermediate between 10.4 and 25.6%, and the higher N25.6%).…”

Relation of ventricular-vascular coupling to exercise capacity in ischemic cardiomyopathy: a cardiac multi-modality imaging study

“…While previous investigators have reported strong correlation between diastolic function [10], arterial stiffness and distensibility with exercise capacity in a varied group of heart failure patients, we postulate that VVC may however, be a better physiological index of cardiac output reserve in response to exercise stress [11].…”

Clinical benefits of integrating cardiac and vascular models

“…The inability of the heart to pump a sufficient amount of blood to meet the demands of the metabolizing tissues, except at elevated filling pressures, causes an alteration of the arterial-ventricular coupling ratio and of the cardiovascular system components [135,136]. Patients with systolic heart failure are characterized by a diminished resting ejection fraction, stroke volume index and left ventricular contractility, associated with increases in heart rate and peripheral vascular resistance [137]. This suboptimal coupling reflects diminished cardiovascular performance and efficiency of the failing heart.…”