2009
DOI: 10.1080/07357900802161062
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T lymphocyte Subsets Determination and DNA Ploidy Analysis in the Differential Diagnosis between Benign and Malignant Ascites

Abstract: Differentiating malignant from benign ascites often leads to confusion and an inability to exclude its multitude of causes in many patients. In the present study, T lymphocyte subsets and DNA ploidy in ascitic fluid were detected by flow cytometer. There were significant differences in T lymphocyte subsets between benign and malignant ascites. For malignant ascites, the sensitivity of DNA aneuploid is 75.6%, the specificity is 79.0%, and the accuracy is 77.6%. The results demonstrate that T lymphocyte subsets … Show more

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Cited by 3 publications
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“…DNA ploidy analysis can signal gross genomic aberrations and has been used to determine prognoses in pre-cancerous and cancerous lesions. 12 According to some authors, DNA flow cytometric parameters have prognostic value in differentiating benign from malignant fluids in the serous membrane cavity. 13 In this study, we explored whether DNA ploidy analysis of ascites fluid can assist in the diagnosis of PC.…”
Section: Introductionmentioning
confidence: 99%
“…DNA ploidy analysis can signal gross genomic aberrations and has been used to determine prognoses in pre-cancerous and cancerous lesions. 12 According to some authors, DNA flow cytometric parameters have prognostic value in differentiating benign from malignant fluids in the serous membrane cavity. 13 In this study, we explored whether DNA ploidy analysis of ascites fluid can assist in the diagnosis of PC.…”
Section: Introductionmentioning
confidence: 99%