The proliferation of smartphones over the past decade has led to the development of a seemingly endless number of digital applications (apps) designed to improve users’ health and fitness. This article addresses the regulation of these apps and provides details about the apps most commonly used by patients in the primary care and diabetes settings. Those described in detail include the American Diabetes Association’s Standards of Care app, apps for blood glucose monitoring and tracking and continuous glucose monitoring, lifestyle apps, a glucagon use app, prescription cost-saving apps, and apps for do-it-yourself automated insulin delivery.