2022
DOI: 10.1016/j.mcpro.2022.100223
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TAILS Identifies Candidate Substrates and Biomarkers of ADAMTS7, a Therapeutic Protease Target in Coronary Artery Disease

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Cited by 10 publications
(2 citation statements)
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“…1 H NMR (600 MHz, DMSO-d 6 ) δ [ppm] = 11.23 (s,1H),8.77 (t,J = 6.36 Hz,1H),8.40 (d,J = 0.98 Hz,1H),7.77 (d,J = 8.02 Hz,2H),7.55 (d,J = 8.02 Hz,2H),1H),3H),6.47 (d,J = 1.96 Hz,1H),1H),1H),3.79 (s,3H). (30). 4-Fluoro-4′-(trifluoromethyl)-[biphenyl]-2-carboxylic acid (194 mg, 0.68 mmol) was dissolved in 3.5 mL of DMF.…”
Section: Imidazolidin-4-yl]methyl}-4′-(trifluoromethyl)[biphenyl]-2-c...mentioning
confidence: 99%
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“…1 H NMR (600 MHz, DMSO-d 6 ) δ [ppm] = 11.23 (s,1H),8.77 (t,J = 6.36 Hz,1H),8.40 (d,J = 0.98 Hz,1H),7.77 (d,J = 8.02 Hz,2H),7.55 (d,J = 8.02 Hz,2H),1H),3H),6.47 (d,J = 1.96 Hz,1H),1H),1H),3.79 (s,3H). (30). 4-Fluoro-4′-(trifluoromethyl)-[biphenyl]-2-carboxylic acid (194 mg, 0.68 mmol) was dissolved in 3.5 mL of DMF.…”
Section: Imidazolidin-4-yl]methyl}-4′-(trifluoromethyl)[biphenyl]-2-c...mentioning
confidence: 99%
“…Collectively, the data suggest that ADAMTS7 inhibition might be a new way to treat CAD and restenosis. 26 ADAMTS7 belongs to a family of 19 secreted zinc metalloproteases 27,28 with proteolytic activity against extracellular substrates 15,29,30 including matrix proteins. 31 The basic ADAMTS structure comprises a pro-domain, a catalytic domain, and an ancillary domain containing thrombospondin repeats which determine substrate specificity and localization.…”
Section: ■ Introductionmentioning
confidence: 99%