Tandem field and laboratory approaches to quantify attenuation mechanisms of pharmaceutical and pharmaceutical transformation products in a wastewater effluent-dominated stream

Zhi, Hui; Mianecki, Alyssa L.; Kolpin, Dana W.; Klaper, Rebecca; Iwanowicz, Luke R.; Lefèvre, Grégory

doi:10.1016/j.watres.2021.117537

Cited by 20 publications

(30 citation statements)

References 73 publications

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“…The rapid attenuation for citalopram was likely due to sorption, 69,70 as we demonstrated in recent research using Muddy Creek stream bed sediments. 43 Other pharmaceuticals persisted along the stream reach with median k -values 4–22 fold lower (0.0098–0.0554 h −1 ; half-life 12–71 h) compared to citalopram (Fig. S.9; Table S.16†).…”

Section: Resultsmentioning

confidence: 99%

“…Due to the relatively limited data available and the fact that we aggregated all concentrations from within the reach (i.e., all sites pooled together), some compound RQs in the simulation are likely quite accurate-while others may be less accurate. For example, citalopram is a rapidlyattenuated compound that is mainly derived from the effluent, 38,43 thus the measured RQs at DS1 are significantly higher than RQs at DS2 (roughly 9-fold; p < 0.0001; Fig. 4).…”

Section: Ecological Risks Quantification and Stochastic Modelingmentioning

confidence: 94%

“…S.10 †) and match our prior results probing mechanistic fates. 43 For example, both measured results and simulation results indicate that citalopram was substantially attenuated (>80%) Environmental Science: Water Research & Technology Paper along the 5.1 km stream reach, while for venlafaxine only moderate attenuation (∼50%) occurred along the stream reach. Citalopram and venlafaxine were selected to represent rapidly-attenuated and moderately-attenuated compounds in the stream reach, respectively.…”

Section: Attenuation Modeling In the Stream And Risks To A Drinking W...mentioning

confidence: 99%

“…This assumption is also reasonable for evaluating changes in risk from effluent-derived chemicals under different storm flow conditions in an effluent-dominated stream, but may not be applicable under all scenarios. Based on our recent work probing attenuation mechanisms in the stream, 43 the singlesegment assumption is likely reasonable because most compounds persist except for citalopram, which rapidly sorbs to bed sediments and concentrations change greatly along the stream reach even over short distances. The corresponding mean and standard deviation of RQs under baseflow conditions and flow discharge from baseflow and all-flow conditions, respectively, were used to generate probabilistic distributions for each input variable (i.e., baseflow RQ, baseflow discharge, and all-flow discharge).…”

Section: Stochastic Risk Modelingmentioning

confidence: 99%

“…34,37 Our prior work demonstrated that Muddy Creek (Coralville, IA) is a representative effluent-dominated stream in a temperate region, and it is also an ideal study site where we conducted long-term monitoring of chemical and hydrologic data. [38][39][40][41][42] In the previous work, we quantified the occurrence/spatiotemporal dynamics and fate mechanisms of pharmaceutical mixtures 38,43 and neonicotinoid insecticides 39 in an effluent-dominated stream under baseflow conditions. Nevertheless, the potential risks to the local ecological system under all-flow conditions and the drinking water source have not yet been evaluated.…”

Section: Introductionmentioning

confidence: 99%

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Modeling risk dynamics of contaminants of emerging concern in a temperate-region wastewater effluent-dominated stream

Zhi

Webb

Schnoor

et al. 2022

Environ. Sci.: Water Res. Technol.

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Section: Resultsmentioning

confidence: 99%

Section: Ecological Risks Quantification and Stochastic Modelingmentioning

confidence: 94%

Section: Attenuation Modeling In the Stream And Risks To A Drinking W...mentioning

confidence: 99%

Section: Stochastic Risk Modelingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Modeling risk dynamics of contaminants of emerging concern in a temperate-region wastewater effluent-dominated stream

Zhi

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Schnoor

et al. 2022

Environ. Sci.: Water Res. Technol.

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The Effects of Wastewater Reuse on Smallmouth Bass (Micropterus dolomieu) Relative Abundance in the Shenandoah River Watershed, USA

Wagner,

McLaughlin,

Faunce

et al. 2024

Enviro Toxic and Chemistry

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Municipal and industrial wastewater effluent is an important source of water for lotic systems, especially during periods of low flow. The accumulated wastewater effluent flows—expressed as a percentage of total streamflow (ACCWW%)—contain chemical mixtures that pose a risk to aquatic life; fish may be particularly vulnerable when chronically exposed. Although there has been considerable focus on individual‐level effects of exposure to chemical mixtures found in wastewater effluent, scaling up to population‐level effects remains a challenging component needed to better understand the potential consequences of exposure in wild populations. This may be particularly important under a changing climate in which wastewater reuse could be essential to maintain river flows. We evaluated the effects of chronic exposure to wastewater effluent, as measured by ACCWW%, on the relative abundance of young‐of‐year (YOY), juvenile, and adult smallmouth bass (Micropterus dolomieu) populations in the Shenandoah River Watershed (USA). We found that increases in ACCWW% in the previous year and during the prespawn period were negatively correlated with the relative abundance of YOY, resulting in an average 41% predicted decrease in abundance (range = 0.5%–94% predicted decrease in abundance). This lagged effect suggests that adult fish reproductive performance may be compromised by chemical exposure during periods of high ACCWW%. No relationships between ACCWW% and juvenile or adult relative abundance were found, suggesting that negative effects of ACCWW% on YOY abundance may be offset due to compensatory mechanisms following higher ACCWW% exposure. Understanding the effects of wastewater effluent exposure at multiple levels of biological organization will help in the development of management strategies aimed at protecting aquatic life. Environ Toxicol Chem 2024;00:1–11. © 2024 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA.

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Advancements in the dominion of fate and transport of pharmaceuticals and personal care products in the environment—a bibliometric study

Ashraf

Ahammad

Chakma

2023

Environ Sci Pollut Res

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The study on the fate and transport of Pharmaceuticals and Personal Care Products, PPCPs (FTP) in the environment, has received particular attention for over two decades. The PPCPs threaten ecology and human health even at low concentrations due to their synergistic effects and long-range transport. The research aims to provide an inclusive map of the scientific background of FTP research over the last 25 years, from 1996 to 2020, to identify the main characteristics, evolution, salient research themes, trends, and research hotspots in the field of interest. Bibliometric networks were synthesized and analyzed for 577 journal articles extracted from the Scopus database. Consequently, seven major themes of FTP research were identified as follows: (i) PPCPs category; (ii) hazardous effects; (iii) occurrence of PPCPs; (iv) PPCPs in organisms; (v) remediation; (vi) FTP-governing processes; and (vii) assessment in the environment. The themes gave an in-depth picture of the sources of PPCPs and their transport and fate processes in the environment, which originated from sewage treatment plants and transported further to sediment/soils/groundwater/oceans that act as the PPCPs’ major sink. The article provided a rigorous analysis of the research landscape in the FTP study conducted during the specified years. The prominent research themes, content analysis, and research hotspots identified in the study may serve as the basis of real-time guidance to lead future research areas and a prior review for policymakers and practitioners.

show abstract

Tandem field and laboratory approaches to quantify attenuation mechanisms of pharmaceutical and pharmaceutical transformation products in a wastewater effluent-dominated stream

Cited by 20 publications

References 73 publications

Modeling risk dynamics of contaminants of emerging concern in a temperate-region wastewater effluent-dominated stream

Modeling risk dynamics of contaminants of emerging concern in a temperate-region wastewater effluent-dominated stream

The Effects of Wastewater Reuse on Smallmouth Bass (Micropterus dolomieu) Relative Abundance in the Shenandoah River Watershed, USA

Advancements in the dominion of fate and transport of pharmaceuticals and personal care products in the environment—a bibliometric study

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