Target identification, and optimization of dioxygenated amide derivatives as potent antibacterial agents with FabH inhibitory activity

Development of boronic acid catalysts for direct amidation of aromatic carboxylic acids using fluorescence-based screening

“…Both aromatic and aliphatic amides are extensively researched across various fields, including pharmaceuticals, 39–41 underscoring the significance of developing catalysts for the direct amidation of aromatic acids with amines. Notably, aromatic and aliphatic carboxylic acids differ in their reactivity towards amines.…”