“…Besides chemotherapy treatment, Port-a-Caths are frequently used for the administration of medications, blood derivatives, parenteral nutrition and specimen collection for laboratory analysis. [1,2,4,5] Regarding the maintenance of the device, the use of heparin or saline solution prevails over other methods of permeability preservation. However, Number of punction Spearma`s rho= 0.72, p < 0.001 maintenance guidelines are followed according to the directions provided by manufacturers, and literature data concerning the type and amount of solution to be employed as well as maintenance intervals are conflicting.…”