Aiming at the problems of low control accuracy and long control time in traditional UAV automatic takeoff ground roll control method, a CFD based UAV automatic takeoff ground roll control method was proposed. Firstly, the flow field calculation formula is defined in the inertial coordinate system, and the rotor flow field generated between UAV and automatic take-off ground roll is solved by CFD method. Then according to the value, the unmanned aerial vehicle (UAV) rotor flow field flow rate from the air spring force, tire spring force, buffer damping force and under the action of ground support, analysis the stress of the roll on the ground, finally on this basis, through the pitching Angle and angular rate control design protection design, airspeed protection design complete automation design, realizes the unmanned aerial vehicle (UAV) automatic take-off and roll control. The simulation results show that the control accuracy of the proposed UAV automatic take-off ground taxiing is 99.5% and the control time is less than 5 s. This method has good control performance and is worth popularizing.