Taxus Wallichiana Zucc. (Himalayan Yew): insights on its antimicrobial and pharmacological activities

Rahman, Shahnaz; Salehin, F; Uddin, Muhammad Jasim; Zahid, A

doi:10.13172/2052-7845-1-1-384

Cited by 9 publications

(7 citation statements)

References 14 publications

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“…The bark of the herb possesses antifertility and antirheumatic properties. The leaves of this plant are beneficial for treating indigestion, epilepsy, fertility, and rheumatism (Rahman, Salehin, Uddin, & Zahid, 2013).…”

Section: Ethnobotanical Usesmentioning

confidence: 99%

“…The species T. wallichiana is considered as an essential medicinal plant, as it contains many therapeutic lead compounds, as shown in Table 1. It exhibits caryophyllene as a significant compound which has been reported to act as an immunomodulatory, antimicrobial, antitumor, analgesic, antipyretic, anticonvulsant, antifeedent, and antiedemic agents (Khan et al, 2006; Nisar et al, 2008; Rahman et al, 2013). The leaf and root part of this species consist of taxoid and which it is capable of destroying human tumor cell lines, However, as compared to other species such as T. baccata , T. brevifolia , and T. cuspidata , T. wallichiana is devoid of “Taxines” (a highly toxic alkaloid) (Bala et al, 1999; Chattopadhyay et al, 2006; Vander‐Velde et al, 1994; Wilson, Sauer, & Hooser, 2001).…”

Section: Pharmacological Activities Of Conifers From Northwestern Himmentioning

confidence: 99%

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Review on essential oils, chemical composition, extraction, and utilization of some conifers in Northwestern Himalayas

Bhardwaj

Islam

Jayasena

et al. 2020

Phytotherapy Research

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Essential oils (EOs) are regarded as alternative therapeutic agents for many diseases. In phytotherapy research areas, it is now well reported that conifers are the rich source of EOs. This review aims to update information on the biological sources and the best extraction processes of the significant constituents along with the traditional and therapeutic properties of the EOs from selected conifers of Himachal Pradesh, Northwestern Himalaya. In the present review, ten conifer species of high values have been selected. Results from several studies suggest that the conifers contain monoterpenes, sesquiterpenes, diterpenes, ketones, alcohols, and esters, which are used in medicines, food products, and cosmetics as well as other commercial and industrial products. Traditionally, the EOs from the conifers have been reported to be used against fever, cough, bronchitis, skin diseases, gastrointestinal disorders, and asthma. The pharmacological studies suggest that these EOs can be used as antirheumatic, antiseptic, antispasmodic, anticancer, anti-inflammatory, antitoxic, aphrodisiac, and astringent agents. It is, therefore, concluded that the EOs from the conifers might be one of the promising tools for the treatment of various diseases. Extensive research is required to ascertain the efficacy of the EOs from unstudied conifers.

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Section: Ethnobotanical Usesmentioning

confidence: 99%

Section: Pharmacological Activities Of Conifers From Northwestern Himmentioning

confidence: 99%

Review on essential oils, chemical composition, extraction, and utilization of some conifers in Northwestern Himalayas

Bhardwaj

Islam

Jayasena

et al. 2020

Phytotherapy Research

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“…Tagetes minuta L./Asteraceae/Genda [65] Sewa River Catchment Area in the north-west Himalaya Herb/Flowers Volatile oil of flower is used Taxus wallichiana Zucc./Taxaceae/ Himalayan Yew [76] India, Nepalese Himalaya Tree/Leaves Leaves extract is given…”

Section: Given Orallymentioning

confidence: 99%

A review on antiviral activity of the Himalayan medicinal plants traditionally used to treat bronchitis and related symptoms

Amber

Adnan

Tariq

et al. 2017

Journal of Pharmacy and Pharmacology

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Objectives Bronchitis is a common respiratory tract infection of humans mainly caused by influenza virus, rhinovirus, adenovirus, coronavirus and respiratory syncytial virus. The aim of this review was to gather fragmented literature on ethnomedicinal plants used against bronchitis in the Himalayan region and their in-vitro validation against bronchitis causing viral pathogens. Key findings Present review contains ethnomedicines of total 55 plants from different countries of the Himalayas. Most of the literature reported was from India followed by Pakistan, China and Nepal. Familiarly used plant families for bronchitis treatment in the Himalayan region were Leguminosae (six plants) and Lamiaceae (five plants). Leaves and roots were the most common parts used in ethnomedicines against bronchitis. Of these 55 plants, only six plants have been studied in vitro against viral pathogens causing bronchitis. Different compounds like monoterpenoids, flavonoids, triterpenoids, iridoid glycosides, sesquiterpenes, benzoic and phenolic compounds were reportedly isolated from these plant extracts having strong antiviral potential. Summary The Himalayan regions possess variety of ethnomedicinal plants used against respiratory diseases, but still there are only few studies related with their in-vitro validation. We invite the attention of researchers for detailed ethnopharmacological and phytochemical studies on unexplored plants used to treat bronchitis for the development of novel antiviral drugs.

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“…The leaves of T. wallichiana is also used to prepare herbal tea for cure of epilepsy and indigestion (9). T. wallichiana is also reported to have immunomodulatory, anti-bacterial, antifungal, analgesic, anti-pyretic and anti-convulsant activities (10). Thus, based on the available reports, an attempt has been made to review the entire domain of beneficial properties of T. wallichiana with special emphasis on its chemical constituents, ethnobotanical uses and pharmaceutical applications.…”

Section: Introductionmentioning

confidence: 99%

Ethnobotanical and pharmacological importance of Taxus wallichiana Zucc.

Sinha¹

2020

Plant Sci. Today

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Taxus wallichiana Zucc. or the Himalayan Yew is a gymnosperm growing along the Himalayan region of Indian and adjoining countries. The plant is extensively used by local people for treatment of various diseases such as fever, headache, diarrhea, fractures, problems of nervous system etc. It also finds usage in Unani system of medicine. The plant is rich in various bioorganic compounds natural products such as hydrocarbons, terpene alcohols, terpenoids (including taxoids), organic acids etc. The plant has been explored for anti-inflammatory, analgesic, antipyretic, anticonvulsant, immunomodulatory, hepatoprotective and anticancer activity with satisfactory outcome. The pharmacological activity of the plant is largely due to the presence of large number of terpenoids. The bioactive constituents present in the plant interacts with a large number of biochemical pathways involved in inflammatory processes, cell division cycles and inhibits a number of enzymes to bring about its protective action against various diseases. In this review, an attempt have been made to highlight the beneficial properties of Taxus wallichiana in various levels of usage starting from its fundamental ethnobotanical use to pharmacological use involving both in-vitro and in-vivo studies. Insights into the molecular mechanisms of action of the active constituents in bringing about the beneficial activity have also been illustrated. The plant can very well become a source of medicine for better management of a large number of diseases including cancer.

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Taxus Wallichiana Zucc. (Himalayan Yew): insights on its antimicrobial and pharmacological activities

Cited by 9 publications

References 14 publications

Review on essential oils, chemical composition, extraction, and utilization of some conifers in Northwestern Himalayas

Review on essential oils, chemical composition, extraction, and utilization of some conifers in Northwestern Himalayas

A review on antiviral activity of the Himalayan medicinal plants traditionally used to treat bronchitis and related symptoms

Ethnobotanical and pharmacological importance of Taxus wallichiana Zucc.

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