Tea tree oil gel for mild to moderate acne; a 12 week uncontrolled, open‐label phase II pilot study

Abstract

This study shows that the use of the tea tree oil products significantly improved mild to moderate acne and that the products were well tolerated.

Complementary and alternative therapy for pediatric acne: A review of botanical extracts, dietary interventions, and oral supplements

“…Several in vivo studies including pediatric patients have demonstrated efficacy in the treatment of acne (Table ), though comparisons to standard acne therapy such as topical retinoids are lacking. Of the four trials including pediatric patients identified here, two were described as doubled blinded, one single (investigator) blinded, and one open label . Only one trial specified that random allocation software was used in randomization of patients .…”

“…Of the four trials including pediatric patients identified here, two were described as doubled blinded, 6,7 one single (investigator) blinded, 8 and one open label. 9 Only one trial specified that random allocation software was used in randomization of patients. 6 True toxicity related to TTO is rare and is limited to experimental animal models or accidental ingestions by children, with no reported deaths.…”

Acne treatment in antiquity: can approaches from the past be relevant in the future?

“…Both treatments reduced the number of inflamed lesions, and interestingly the TTO group showed significantly less scaling, pruritus, and dryness compared to BP . In fact, the effects of tea tree oil on acne have been evaluated in a number of clinical trials . Interestingly, when the effect of TTO on hypersensitivity reactions was examined, it had a strong inhibitory effect on histamine release .…”

“…30,31 In fact, the effects of tea tree oil on acne have been evaluated in a number of clinical trials. 30,[32][33][34][35][36] Interestingly, when the effect of TTO on hypersensitivity reactions was examined, it had a strong inhibitory effect on histamine release. 26,37 This may help with the redness and irritation associated with inflammatory acne.…”

Alternative Medicine for Hair Loss

“…Although the loss of hair is not a life-threatening condition, the loss of hair at an early age or sudden onset hair loss may cause serious psychological distress, thus it may directly affect the quality of life negatively [1,3]. For this reason, patients with suffering from hair loss should be considered finically in order Similarly, using of CAM is quite often among patients suffering from dermatologic disorders such as acne, atopic dermatitis, psoriasis, dermatophytes, actinic keratosis, vitiligo, hair loss, cosmetic indications, melanoma, and lupus erythematosus [20][21][22][23][24][25][26][27]. A survey data from UK indicated that 35-69% of patients who have various skin diseases have used CAM in their lifetime [27].…”