Technetium 99m Single Positron Emission Computed Tomography Scanning for Assessing Mandible Invasion in Oral Cavity Cancer

Abstract

Preoperative SPECT scanning used in combination with clinical examination, CT scanning, and Panorex x-rays to assess patients at risk for mandible involvement by oral cavity cancer can improve the accuracy of predicting bone invasion and help in appropriate treatment planning so as to safely reduce the proportion of disease-free jaws resected.

Bone invasion in oral cancer patients: A comparison between Orthopantamograph, conventional computed tomography, and single positron emission computed tomography

“…[7] In 2001, observations on SPECT scanning demonstrated an 87% overall accuracy in predicting bone invasion. [15] SPECT scanning was more sensitive (95%) and notably demonstrated a considerable improvement in specificity (72%).…”

Contemporary management of cancer of the oral cavity

“…In general, bone involvement is usually underestimated by CT, whereas with MRI and bone scintigraphy with SPECT the involvement is often overestimated [33, 34]. A negative MRI or bone scan excludes mandibular invasion in all likelihood.…”

Emission Computed Tomography for the Diagnosis of Mandibular Invasion by Head and Neck Cancers: A Systematic Review and Meta-Analysis

“…After retrieving the full text, 17 studies were included (Fig 1). [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] …”