2023
DOI: 10.1002/mp.16729
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Technical note: Impact of dose voxel kernel (DVK) values on dosimetry estimates in 177Lu and 90Y radiopharmaceutical therapy (RPT) applications

Rachele Danieli,
Daniele Pistone,
Jonathan Tranel
et al.

Abstract: BackgroundRadiopharmaceutical therapy (RPT) is an increasingly adopted modality for treating cancer. There is evidence that the optimization of the treatment based on dosimetry can improve outcomes. However, standardization of the clinical dosimetry workflow still represents a major effort. Among the many sources of variability, the impact of using different Dose Voxel Kernels (DVKs) to generate absorbed dose (AD) maps by convolution with the time‐integrated activity (TIA) distribution has not been systematica… Show more

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