Technical Validation and Usability of a Portable Ultrasound-Based System for Carotid Assessment of Vascular Ageing: A Pilot Study

Francesconi, Martina; Martina, Maria Raffaella; Armenia, Silvia; Buzzelli, Andrea; Franco, Gregorio Di; Gemignani, V.; Bianchini, Elisabetta; Bruno, Rosa María

doi:10.1016/j.hlc.2021.06.530

Cited by 3 publications

(1 citation statement)

References 25 publications

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“…Compared with the ultrasound imaging system, the DUT revealed an accuracy greater than 91% regarding carotid stiffness evaluation. This is an acceptable agreement between two noninvasive vascular stiffness monitors [25,26]. Moreover, when compared with SphygmoCor, the DUT has met the criteria (mean difference = 0.06 ± 0.31 m/s) for an ‘excellent’ grade of accuracy for cfPWV, as stated by the ARTERY Society guidelines [15].…”

Section: Discussionmentioning

confidence: 68%

Image-free ultrasound for local and regional vascular stiffness assessment: the ARTSENS Plus

Nabeel

Kiran

Joseph

2022

Journal of Hypertension

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Objective: The combined assessment of vascular health markers is crucial for identifying the cumulative burden of vascular risk factors early on, as well as the extent of vascular aging for effective prediction of future cardiovascular events. This work addresses the need for a currently nonexistent device or system that facilitates such combined assessment in clinical practice and large-scale screening settings. We report an image-free ultrasound device -ARTSENS Plus -developed for the measurement of local and regional arterial stiffness, central and peripheral blood pressure (BP), and vessel dimensions, all in one examination.Methods: A preclinical study on 90 asymptomatic individuals verified the device's functionality under ARTERY Society guidelines. The device's accuracy of stiffness measures was validated against the reference measures. Results:The interoperator and intraoperator variability was less than 7%. Carotid artery's lumen diameter and local stiffness indices and carotid-femoral regional pulse wave velocity showed excellent agreement with the references (absolute errors were less than 4.1, 9, and 4.1%, respectively). The carotid SBP was 10.02% lower than that of the brachial artery, as expected. Conclusion:The study demonstrated the device's ability to perform an effortless and reliable evaluation of the local and regional vascular stiffness and central BP with an accuracy that meets clinical standards.

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Section: Discussionmentioning

confidence: 68%

Image-free ultrasound for local and regional vascular stiffness assessment: the ARTSENS Plus

Nabeel

Kiran

Joseph

2022

Journal of Hypertension

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Vascular Ageing: A Key Frontier in the Fight Against Cardiovascular Disease

Climie¹,

Gregory

Denniss

et al. 2021

Heart, Lung and Circulation

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Developing technologies to assess vascular ageing: a roadmap from VascAgeNet

Zanelli,

Agnoletti,

Alastruey

et al. 2024

Physiol. Meas.

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Vascular ageing is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular risk, with potential applications in disease diagnosis and prognosis, and for guiding treatments. However, vascular ageing is not yet routinely assessed in clinical practice. A key step towards this is the development of technologies to assess vascular ageing. In this Roadmap, experts discuss several aspects of this process, including: measurement technologies; the development pipeline; clinical applications; and future research directions. The Roadmap summarises the state of the art, outlines the major challenges to overcome, and identifies potential future research directions to address these challenges.

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Technical Validation and Usability of a Portable Ultrasound-Based System for Carotid Assessment of Vascular Ageing: A Pilot Study

Cited by 3 publications

References 25 publications

Image-free ultrasound for local and regional vascular stiffness assessment: the ARTSENS Plus

Image-free ultrasound for local and regional vascular stiffness assessment: the ARTSENS Plus

Vascular Ageing: A Key Frontier in the Fight Against Cardiovascular Disease

Developing technologies to assess vascular ageing: a roadmap from VascAgeNet

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