Abstract:In this study, we investigated the response of DNA modified carbon nanotubes in the presence of thrombin and albumin. Interactions between DNA aptamers and carbon nanotubes were analyzed by Raman spectroscopy and by measuring the resistance of the construct after each step of biosensor assembly. It was shown that aptamer binding to carbon nanotubes decreased the G band intensity and lowered the resistance of the sensor structure. The responses of the sensor exposed to thrombin and albumin differed substantiall… Show more
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