During the pandemic outbreak of COVID-19, the important role of plastic becomes evident since vital equipment such as respirators have plastic parts, as well as personal protective equipment (PPE), which avoids the transmission of the SARS-CoV-2 virus, is made of plastic. So, plastic during a pandemic is considered a life savior in the struggle against the virus. However, the same material that is a protector becomes a polluter when inadequately disposed of in the environment, generating or worsening socio-environmental problems, such as pollution of water bodies by plastic. This work proposes a reflection about the role and the importance of plastic in our society, bringing an overview of its main applications and consequences during the COVID-19 pandemic, correlating its use with aspects related to environmental problems and public health. Some questions revolving around the concerns caused by plastic pollution are posed, and some possible solutions to the problems are outlined.