In order to increase the healthy life expectancy and reduce the total temporary disability of the working population, special attention should be paid to the prevention of diseases. The modern level of scientific and technical progress allows to increase the efficiency of solving the problems of preventive medicine through the application of digital technologies. Digital preventive medicine must become an independent research field. The article characterizes the status and prospects of digitalization of key areas of preventive medicine with an emphasis on technologies to preserve the health of the working population. The current issues of digitalization of preventive medicine and priorities of its further development are identified.