Industrial-technological innovation (ITI) has far-reaching significance for China’s sustainable development. In this study, we construct an ITI model to analyze the impact of communication barrier and spillover effects in ITI system from the perspective of system by means of system dynamics. Statistical data of smartphone industry were collected to verify the authenticity of the model, which show that the model has higher goodness of fit with the real-world. Simulation experiments were carried out and the results showed that: (1) Spillover effects have obvious effects on ITI in both positive and negative radiation directions, and deeper exchanges and cooperation should be encouraged to carry out among firm. (2) Communication barrier play an important role in regulating ITI. Under the condition of non-barrier and complete-barrier, the completion time of the whole process has increased by 76.5%, it is urgent to reduce communication carrier. The research puts forward suggestions to help improve ITI from institutional, market, and government.