Telomere length and genetic variations affecting telomere length as biomarkers for facial regeneration with platelet‐rich fibrin based on the low‐speed centrifugation concept

Abstract

Telomere length (TL) was related to patient perceived facial skin appearance. In addition, genetic variations affecting TL were related to the final outcomes (number of sessions and improvements of FACE-Q results) and may be a useful biomarker for future regenerative procedures performed with PRF for facial regeneration.

Injectable platelet‐rich fibrin for facial rejuvenation: A prospective, single‐center study

“…To the best of our knowledge, only two studies have used the FACE-Q to evaluate patient-reported outcomes following use of PRP or PRF monotherapy for facial rejuvenation. 43,44 In one study, Lee and colleagues showed improvement in participant satisfaction with overall facial appearance and cheeks following a single injection of PRF 43 while in the other study Nacopoulos and colleagues that reported an improvement in the satisfaction with skin questionnaire following several sessions of injectable PRF treatment. 44 To our knowledge, the clinical use of injectable PRF for facial aesthetics has only been previously reported in a single study.…”

“…In view of the low baseline score for skin adverse effects (29 of 100), the lack of a statistically significant improvement is not unexpected. To the best of our knowledge, only two studies have used the FACE‐Q to evaluate patient‐reported outcomes following use of PRP or PRF monotherapy for facial rejuvenation 43,44 . In one study, Lee and colleagues showed improvement in participant satisfaction with overall facial appearance and cheeks following a single injection of PRF 43 while in the other study Nacopoulos and colleagues that reported an improvement in the satisfaction with skin questionnaire following several sessions of injectable PRF treatment 44 …”

Lower facial regeneration with a combination of platelet‐rich fibrin liquid matrices based on the low speed centrifugation concept‐Cleopatra technique

“…Moreover, genetic factors could be utilized as biomarkers or predictors for regenerative protocols with PRF in the field of facial esthetics. 17 To our knowledge, this is the first published study to show a clinically significant benefit of liquid PRF matrices as a single treatment modality on facial regeneration. Furthermore, as it is expected due to their autologous nature, these matrices are relatively safe with minimal and self-limited adverse effects.…”

A Personalized Nutrition Plan Improves Outcomes of Facial Regeneration With Platelet-rich Fibrin Liquid Matrixes

“…Oncological Hospital of Ki sia, Athens, Greece (No 1/26/09/2016) and the patients signed an informed consent prior to their treatment. All patients were treated by the same experienced physician (CN) using a standard protocol described in more detail in previous publications (4,5). Brie y, four sessions of PRF treatments were offered with 2-to 3-week intervals.…”

“…(1)(2)(3). Platelet-rich brin liquid matrices based on the low speed centrifugation concept have shown effectiveness in facial regeneration (4,5) and are being increasingly applied in facial aesthetics either alone or in combination with other techniques.…”