Temporal and spatial resolution in foveal vision of multiple sclerosis patients

Abstract

Deficits of spatial and temporal resolution were compared in a group of 49 definite multiple sclerosis(MS) patients showing no major evidence of previous optic neuritis attack but representative of the population of the Belgian National MS Centre as to age and the most important disease variables. Resolution in the two domains was measured foveally with forced-choice staircase psychophysical procedures using Landoldt C and double flash stimuli, respectively. The two measurements were equally sensitive to MS-induced deficits and did not exhibit cross-sensitivity. Since discrete deficits of either kind were equally prevalent and outnumbered combined deficits, this suggests a nonselective but nonuniform destruction of M and P visual pathway function in these patients.

The Visual (dis)Function in Neurological Diseases

“…Additionally, spatial and temporal resolutions are also affected since the demyelination insult impairs the brainstem and also subcortical areas [123][124][125][126][127] evidenced by imaging studies [128]. (FM-100).…”

Diferenças na detecção de frequências espaciais e radiais em crianças

“…Em termos gerais, a FSC possibilita uma avaliação teórica e clínica do sistema visual humano (Adams & Courage, 2002;John, 1997;Montés-Micó & Ferrer-Blasco, 2001;Vleugels, van Nunen, Lafosse, Ketelaer & Vandenbussche, 1998;Wilson, Levi, Maffei, Rovamo & De Valois, 1990).…”

Mesopic Visual Contrast Sensitivity in Patients with Major Depression

“…Visual CS is one of the most widely used tools in the diagnosis and theoretical and clinical evaluation of changes in visual perception and alterations in the central nervous system (Wesner & Tan, 2006) caused by disorders or diseases, such as schizophrenia (Slaghuis & Thompson, 2003), amblyopia (Polat, Sagi, & Norcia, 1997), cataracts (Elliott & Situ, 1998), mercury poisoning (Ventura et al, 2005), stroke (Santos & Andrade, 2012;Santos, Andrade, & Fernandez Calvo, 2013), and Alzheimer's and Parkinson's diseases (Polat et al, 1997;Akutsu & Legge, 1995;Bour & Apkarian, 1996;Vleugels et al, 1998).…”