“…While the primary focus of BoNT therapy to the orbicularis oculi is for the treatment of crow's feet, the orbicularis oculi is also the most powerful depressor of the brow and can contribute greatly to reshaping the brow and upper face through neuromodulation. 17,18 Thus, aesthetic treatment of the lateral orbital region should involve consideration of the hyperdynamic lines and brow reshaping. Although single-point limited dosing at the lateral brow margin may provide some benefit in elevating brow position, it is important to keep in mind that the entire lateral orbicularis oculi is responsible for brow depression and, as shown in the senior author's previous work, 17,18 treatment of this large and powerful depressor can have a profound impact on brow position.…”