Temporal persistence and long-term effect on noninvasive prenatal testing by residual fetal cell-free DNA of demised co-twin after selective fetal reduction in dichorionic diamniotic twin pregnancies
Abstract:Objectives: To determine the temporal persistence of residual cell-free DNA (cfDNA) of deceased co-twin in maternal circulation after selective fetal reduction and evaluate its long-lasting effect on noninvasive prenatal testing (NIPT) results. Design: Prospective observational study Setting: The Third Affiliated Hospital of Guangzhou Medical University Population: Dichorionic diamniotic twins (n=5) underwent selective fetal reduction of a co-twin with trisomy. Methods: With consent, maternal blood was collect… Show more
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