Temporal Trends (over 30 Years), Clinical Characteristics, Outcomes, and Gender in Patients ≤50 Years of Age Having Percutaneous Coronary Intervention

Khawaja, Farhan J.; Rihal, Charanjit S.; Lennon, Ryan J.; Holmes, David R.; Prasad, Abhiram

doi:10.1016/j.amjcard.2010.10.044

Cited by 56 publications

(53 citation statements)

References 25 publications

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“…Obesity rates among MI patients below 45 years of age have been estimated at 30-58% [12]. The Coronary Artery Risk Development in Young Adults (CARDIA) study [25] highlighted the problem of obesity among young Americans, and adverse trends regarding overweight and obesity were also noted among young Poles. Among CAD risk factors taken into account in the present study, BMI ≥ 25 kg/m 2 has been considered one of the most important in addition to tobacco smoking and hyperlipidaemia, which supports the notion that we are witnessing a global obesity epidemic in the 21 st century.…”

Section: Discussionmentioning

confidence: 99%

Clinical and angiographic characteristics of coronary artery disease in young adults: a single centre study

Maroszyńska-Dmoch

Wożakowska−Kapłon

2016

Kardiol Pol

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A b s t r a c tBackground: Coronary artery disease (CAD) in young adults under 40 years of age is a growing medical, social, psychological and economical problem, related to the prevalence of civilization-related diseases and unhealthy lifestyle. The problem of CAD in young people has not been characterised as well as in older individuals, as the available data mostly come from case reports and small series, often related to genetic aspects and familial occurrence of the disease. Aim:To assess clinical and angiographic characteristics of young adults with CAD and to evaluate in-hospital and long-term mortality in this patient group. The study combined a retrospective and a prospective approach.Methods: A total of 239 patients aged 40 years or younger who underwent coronary angiography (CAG) in the Swietokrzyskie Centre of Cardiology in Kielce in [2001][2002][2003][2004][2005][2006][2007][2008] were included in this study. Demographic characteristics, risk factor profile, laboratory test results, electrocardiographic and echocardiographic findings, CAG findings, and in-hospital mortality were assessed retrospectively in the selected groups. During the second stage of the study, clinical and mortality data were obtained prospectively in 130 patients (54.4% of the study group) during up to 5 years of follow-up. Results:The mean patient age was 35.1 ± 4.4 years. Men made up 86.2% of the study sample, and the proportion of rural area residents was 54.8%. Among young patients with acute coronary syndromes (ACS), the most common presentation (52.8%) was ST segment elevation myocardial infarction (STEMI). Angiographically normal coronary arteries were found in 37.2% of CAD patients and in 16.9% of patients with the diagnosis of ACS. The mean degree of coronary artery lumen stenosis was 75.4% in the group with significant atherosclerotic coronary lesions (50-90%) and 95.9% in the group demonstrating a critical coronary obstruction (≥ 90%). Single-vessel disease was identified in 61.9% of patients with a positive result of CAG (stenosis > 50%, CORO(+) group). The most common location of significant atherosclerotic coronary lesions was the left anterior descending artery (61.6%) followed by the right coronary artery (27.4%). The most prevalent conventional cardiovascular risk factors were lipid abnormalities, cigarette smoking and an increased body mass index ≥ 25 kg/m 2 , followed by a family history of CAD and hypertension. The proportion of patients with abnormal lipid profile, cigarette smoking and overweight or obesity was particularly high in the CORO(+) group (85.6%, 83.9%, and 64.4%, respectively). In-hospital mortality rate was low, at 0.7% among ACS patients. Long-term mortality during up to 5 years of follow-up was not so favourable, at 7.75% in ACS patients and 8.5% in the CORO(+) group. Conclusions:The population of young patients with CAD is predominantly male, rural, and characterised by a low socioeconomic status. The aetiology of CAD in this patient group differs significantly from that in older patients a...

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Section: Discussionmentioning

confidence: 99%

Clinical and angiographic characteristics of coronary artery disease in young adults: a single centre study

Maroszyńska-Dmoch

Wożakowska−Kapłon

2016

Kardiol Pol

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“…Wyniki długofalowej obserwacji naukowców z Mayo Clinic, obejmującej pacjentów przed 50. rokiem życia hospitalizowanych z powodu choroby wieńcowej, u któ-rych wykonano przezskórną interwencję wieńcową (PCI, percutaneous coronary interventions), potwierdzają narastające z wiekiem obciążenie klasycznymi czynnikami ryzyka sercowo-naczyniowego, takimi jak cukrzyca, otyłość, nadciśnienie tętnicze i hiperlipidemia [6].…”

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Edukacja zdrowotna pacjentów z chorobami układu sercowo-naczyniowego

Martelli

2017

Folia Cardiologica

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StreszczenieChoroby układu sercowo-naczyniowego są główną przyczyną zgonów w Polsce oraz w pozostałych krajach Europy. Należą one do grupy chorób przewlekłych. Jak wykazują wyniki badań epidemiologicznych, zależą od występowania wielu czynników ryzyka -modyfikowalnych i niemodyfikowalnych. Do najważniejszych z grupy czynników modyfikowalnych zalicza się otyłość, hiperlipidemię, nadciśnienie tętnicze, cukrzycę, palenie tytoniu, małą aktywność fizyczną oraz czynniki psychospołeczne.Działania edukacyjne prowadzone u pacjentów z rozpoznanymi chorobami układu sercowo-naczyniowego mają na celu wyeliminowanie lub modyfikację istniejących czynników poprzez przekazanie wiedzy na temat właściwego postępowania oraz zmotywowanie do przestrzegania wdrażanych zaleceń terapeutycznych. Jak pokazują liczne doniesienia naukowe, wdrażanie interwencji edukacyjnych z zastosowaniem metod ustnych i pisemnych oraz złożonych programów rehabilitacyjno-edukacyjnych sprzyja podniesieniu poziomu wiedzy, co może zwiększyć efektywność zastosowanej terapii.Słowa kluczowe: edukacja zdrowotna, choroby układu sercowo-naczyniowego Cardiologica 2016; 11, 6: 519-524 Folia

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“…The incidence of hypertension in young patients with AMI seems to have increased over the years. Garoufalis et al 14 22 We did not observe any significant change in the incidence rate of risk factors, which may be due to a relatively short study period.…”

Section: Data Collectionmentioning

confidence: 67%

Treatment and outcomes of patients under 40 years of age with acute myocardial infarction in Poland in 2009-2013 (analysis from PL-ACS Registry)

Trzeciak¹,

Gierlotka²,

Poloński³

et al. 2017

Polish Archives of Internal Medicine

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Temporal Trends (over 30 Years), Clinical Characteristics, Outcomes, and Gender in Patients ≤50 Years of Age Having Percutaneous Coronary Intervention

Cited by 56 publications

References 25 publications

Clinical and angiographic characteristics of coronary artery disease in young adults: a single centre study

Clinical and angiographic characteristics of coronary artery disease in young adults: a single centre study

Edukacja zdrowotna pacjentów z chorobami układu sercowo-naczyniowego

Treatment and outcomes of patients under 40 years of age with acute myocardial infarction in Poland in 2009-2013 (analysis from PL-ACS Registry)

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