Biomechanics is the study of mechanics applied to living beings, it analyzes loads, stress, tension, movement, size, shape, and structure of the body. The temporomandibular joint in physiological states is subject to the interaction of various bone (jaw and temporal), nervous, cartilaginous, and muscular components. When there is an alteration in any of the components, normal biomechanics are affected. Knowing in detail how each element works individually and is essential for the diagnosis and treatment of the different pathologies of the temporomandibular joint. The reconstructive procedures must carefully assess all these factors to achieve long-term success. The purpose of this chapter is to analyze the temporomandibular joint encompassing anatomy, physiology with a biomechanical approach for its diagnosis and treatment.