Tesla valve-assisted biosensor for dual-mode and dual-target simultaneous determination of foodborne pathogens based on phage/DNAzyme co-modified zeolitic imidazolate framework-encoded probes

Advances in electrochemical-optical dual-mode biosensors for detection of environmental pathogens

“…More recently, the same group reported an innovative nanoprobe for determining Salmonella typhimurium and E. coli simultaneously using dual-mode signals (electrochemical and fluorescent signals). 93 As displayed in Fig. 5, an amino-modified zeolitic imidazolate framework (ZIF-8) that encapsulates ferrocene or methylene blue was employed to integrate with different phages and DNAzymes to construct the encoded signal nanoprobes.…”

Recent progress on DNAzyme-based biosensors for pathogen detection

“…They also designed a method using two different phages to recognize the corresponding bacteria in two areas on the platform. 158 They created dual-signal biosensors using CLICK 17 DNAzyme for the detection of Vibrio parahaemolyticus . 159 Moreover, they developed a microfluidic chip to detect Staphylococcus aureus .…”