2019
DOI: 10.1002/jmri.26921
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Test–Retest Reliability of the Brain Metabolites GABA and Glx With JPRESS, PRESS, and MEGA‐PRESS MRS Sequences in vivo at 3T

Abstract: Background The optimization of magnetic resonance spectroscopy (MRS) sequences allows improved diagnosis and prognosis of neurological and psychological disorders. Thus, to assess the test–retest and intersequence reliability of such MRS sequences in quantifying metabolite concentrations is of clinical relevance. Purpose To evaluate the test–retest and intersequence reliability of three MRS sequences to estimate GABA and Glx = Glutamine+Glutamate concentrations in the human brain. Study Type Prospective. Subje… Show more

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Cited by 43 publications
(65 citation statements)
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“…Measurement agreement in the dlPFC was also strong. Thresholds for interpreting CVs are rarely discussed in the MRS literature, but the current averaged CVs were far below those previously used (eg, 20% used by Baeshen et al 8 ). Additionally, BA plots revealed few outliers with no systematic trends in measurement error, further indicating strong agreement.…”
Section: F I G U R Ementioning
confidence: 62%
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“…Measurement agreement in the dlPFC was also strong. Thresholds for interpreting CVs are rarely discussed in the MRS literature, but the current averaged CVs were far below those previously used (eg, 20% used by Baeshen et al 8 ). Additionally, BA plots revealed few outliers with no systematic trends in measurement error, further indicating strong agreement.…”
Section: F I G U R Ementioning
confidence: 62%
“…Averaged CVs showed moderate agreement, and BA plots revealed few outliers and no bias in measurement error. Meanwhile, rACC ICCs were in the low‐moderate range 8,55,56 …”
Section: Discussionmentioning
confidence: 98%
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