2009
DOI: 10.1055/s-0029-1210593
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Testosterone-Induced Oestrous Cycle Blockade in the Rat: No Evidence for Prolactin Involvement

Abstract: The relation between testosterone-induced oestrous cycle disruption and prolactin (Prl) secretion was studied in the female rat. Testosterone propionate (TP) injection on dioestrus 2 (day 0) of 4-day cycles induced cycle interruption for 12 days. A diurnal pattern of Prl secretion was observed from day 1 to day 6 with high levels in the afternoon and low levels in the morning. Cycle interruption also occurred in TP treated females given a dose of bromocriptine (BRC) known to completely block Prl secretion. Imp… Show more

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