Tetrapeptide-based mimotope affinity monolith for the enrichment and analysis of anti-HER2 antibody and antibody-drug conjugate

Mimotope peptide modified pompon mum-like magnetic microparticles for precise recognition, capture and biotransformation analysis of rituximab in biological fluids

“…For instance, polymer‒peptide conjugates with long circulation time were engineered for tumor targeted delivery to improve therapeutic efficacy 2 , 3 or self-assembled peptide nanomaterials were designed for cancer diagnostics and therapy 4 , 5 . In particular, with the rapid development of precision medicine and biopharmaceuticals, peptides as important recognition elements were also used to construct biosensors for clinical diagnosis and therapeutic monitoring 6 , 7 , 8 or fabricate sorbents for the purification and bioanalysis of therapeutic proteins in bioengineering 9 , 10 , 11 , 12 , 13 , 14 . Therefore, the exploitation of peptide based biomaterials with desired properties will certainly gain more attention in future.…”