Teucrium polium L. extract adsorbed on zinc oxide nanoparticles as a fortified sunscreen

Abstract

Introduction:Zinc oxide nanoparticles (ZnOn) have been used as carriers and sun-protecting agents for Teucrium polium L. extract to enhance sun protection. ZnOn was synthesized by hydrolyzing zinc acetate using sodium hydroxide with mean particle diameter less than 500 nm.Materials and Methods:Top flowerings of T. polium L. were extracted by percolation method with petroleum ether, chloroform, and 80% methanol consecutively. Methanolic extract was lyophilized and used as a flavonoid-rich fraction. Sunscreen was prepared by the reconstitution of 0.5 g of the lyophilized extract in water and mixing with 0.5 to 2 g zinc-oxide (ZnO). Sun protection factor (SPF) of the aqueous extract of T. polium, the prepared gel, as well as the zinc oxide suspension alone and in combination with each other was determined spectrophotometrically based on a modified Transpore® tape method.Results and Conclusion:Obtained results showed that the T. polium extract has a wide band of ultraviolet radiation (UV) spectrum absorption ranging from 250 nm to 380 nm. SPF of the combination product in the ultraviolet B (UVB) area was greater than 80, revealing a synergistic action between ZnO and T. polium. The adsorption of flavonoids of T. polium on Zinc-oxide nanoparticles (ZnOn) slowed down their release thereby lengthening their persistence on the skin and contributing to further duration of action.

Proliferation and In Vitro Wound Healing Effects of the Microniosomes Containing Narcissus tazetta L. Bulb Extract on Primary Human Fibroblasts (HDFs)

“…Two hundred μl of aluminum chloride 10% and after 5 min, 1 ml sodium hydroxide 1 mol litre −1 were added to the mixture. The solution was mixed well and the absorbance was measured against prepared reagent blank at 510 nm with ELISA reader (Biotek, USA) [26]. All quantitative experiments were performed triplicate and the results were shown as mean ± SD.…”

Comprehensive Analysis of Phytochemical Composition, Antioxidant Potential, and Antibacterial Activity of T. polium

“…Current research on the chemical composition of T. polium, based on chromatographic analysis of the extracts [6], reveals that this genus is composed of various chemical substances. It is rich in secondary metabolites such as polyphenols, flavonoids, tannins, and coumarins, well known for their therapeutic properties.…”