“…Studies have shown that the pressure in the common bile duct, the basal pressure of the sphincter of Oddi, the peak pressure and the contractile frequency are significantly reduced one week after dilatation of the papilla [19,27,28] . Two studies of the histology of the papilla after dilatation, one performed in pigs [29] and the other in humans [30] , demonstrated no disruption of the smooth muscle or distortion of the architecture, although inflammation and mild or moderate fibrosis was observed in the majority of cases.…”