2003
DOI: 10.1046/j.1464-410x.2003.04094.x
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The aetiology, pathophysiology and management of chronic orchialgia

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Cited by 65 publications
(48 citation statements)
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“…Similarly reduced rauwolscine sensitivity was observed in the isolated vas of a mutant mouse strain (D79N) which harbours a malfunctioning ∝-2a adrenoceptor. These results suggest that vas deferens of subjects who present with intractable chronic testicular pain exhibit a reduction in the pre-junctional autoinhibition mechanism [5][6][7][8].…”
Section: Review Articlementioning
confidence: 99%
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“…Similarly reduced rauwolscine sensitivity was observed in the isolated vas of a mutant mouse strain (D79N) which harbours a malfunctioning ∝-2a adrenoceptor. These results suggest that vas deferens of subjects who present with intractable chronic testicular pain exhibit a reduction in the pre-junctional autoinhibition mechanism [5][6][7][8].…”
Section: Review Articlementioning
confidence: 99%
“…Antibiotics are administered on the presumption that the pain may be secondary to some unindentifi ed infection. Non-steroidal antiinfl ammatory drugs are prescribed along with the antibiotics; they reduce the local infl ammatory process and thereby relieve the pain [8]. Alpha-adrenergic antagonists A trial of α-1 blocker should be given to patients who do not respond to conservative management and wish to avoid the surgical options.…”
Section: Non-surgical Managementmentioning
confidence: 99%
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“…Pain syndromes without specific causes, including orchalgia, urethral syndrome, prostatodynia, proctodynia and others, are well described, and a multidisciplinary approach to management has been recommended [1][2][3][4][5][6]. Urological investigations are aimed at excluding organic pathology to exclude conditions such as epididymitis, epididymal cysts, varicoceles, hydroceles and of course testicular tumours.…”
Section: Introductionmentioning
confidence: 99%