The Ahmed Versus Baerveldt Study

Christakis, Panos G.; Kalenak, Jeffrey W.; Tsai, James C.; Zurakowski, David; Kammer, Jeffrey A.; Harasymowycz, Paul; Mura, Juan J.; Cantor, Louis B.; Ahmed, Iqbal Ike K.

doi:10.1016/j.ophtha.2016.06.035

Cited by 273 publications

(150 citation statements)

References 31 publications

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“…67 In the paper by Seah et al, 12 Allan et al, 11 and our study, no significant difference was found in medication use at 1 year. No significant differences in mean VA were noted between groups in either of the prospective randomized studies comparing Baerveldt implants to Ahmed implants or in the retrospective studies by Seah, Allan, or our investigation.…”

Section: Discussionmentioning

confidence: 40%

“…67 The 5-year results of the ABC study showed a mean IOP in the Ahmed group of 14.7 (± 4.4) mm Hg and 12.7 (± 4.5) mm Hg in the Baerveldt group (p = 0.015). 6 The AVB study’s 5-year results showed a mean IOP of 16.6 (± 5.9) mm Hg for the Ahmed and 13.6 (± 5.0) mm Hg for the Baerveldt (p = 0.001) groups.…”

Section: Discussionmentioning

confidence: 99%

“…6 The AVB study’s 5-year results showed a mean IOP of 16.6 (± 5.9) mm Hg for the Ahmed and 13.6 (± 5.0) mm Hg for the Baerveldt (p = 0.001) groups. 7 As well as having a difference in implant size, there is also a difference in timing of aqueous reaching the episcleral plate area because the Ahmed implant is valved and delivers aqueous immediately to the plate, whereas the Baerveldt is generally occluded for several weeks postoperatively to prevent overdrainage.…”

Section: Discussionmentioning

confidence: 99%

“…No significant differences in mean VA were noted between groups in either of the prospective randomized studies comparing Baerveldt implants to Ahmed implants or in the retrospective studies by Seah, Allan, or our investigation. 67910 …”

Section: Discussionmentioning

confidence: 99%

“…67 Although this difference may be related to the larger surface area of the Baerveldt implant, it should also be noted that the Ahmed implant is valved and delivers aqueous to the episcleral plate area immediately after surgery, whereas the Baerveldt is a nonvalved implant and is generally occluded until a capsule forms over the plate. This difference in the timing of aqueous delivery has been suggested by some as a possible factor influencing the thickness of the capsule formed over the plate due to the increased cytokines in the aqueous in the early postoperative period.…”

Section: Introductionmentioning

confidence: 99%

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Retrospective Comparison of Intermediate-term Efficacy of 350 mm2 Glaucoma Drainage Implants and Medium-sized 230—250 mm2 Implants

Meyer

Rodgers

Zou

et al. 2017

Journal of Current Glaucoma Practice

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AimTo compare the intermediate-term efficacy of a large surface area Baerveldt 350 mm2 glaucoma drainage device (GDD) with medium surface area implants (Baerveldt 250 mm2 and Molteno 3, 230, or 245 mm2).DesignThis is a retrospective, nonrandomized comparative trial.Materials and methodsA total of 94 eyes of 94 patients of mixed glaucoma diagnoses without any prior glaucoma surgical procedures and who had undergone a glaucoma drainage implant surgery with either a large Baerveldt 350 mm2 GDD or a medium-sized GDD (Baerveldt 250 mm2 or Molteno 230 or 245 mm2) were reviewed for intraocular pressure (IOP), number of glaucoma medications, and visual acuity (VA) preoperatively, and at 1, 2, and 3 years postprocedure.ResultsNo significant differences were found in mean IOP, number of glaucoma medications used, and VA at 1, 2, and 3 years postoperatively. The rate of additional glaucoma procedures was similar between the two groups.ConclusionThere is no clear evidence that a larger implant surface area beyond 230 to 250 mm2 is advantageous in providing intermediate-term IOP control.Clinical significanceIt may be technically easier to surgically place a GDD that does not need to have its wings placed underneath the recti muscles, and the IOP results are similar.How to cite this articleMeyer AM, Rodgers CD, Zou B, Rosenberg NC, Webel AD, Sherwood MB. Retrospective Comparison of Intermediate-term Efficacy of 350 mm2 Glaucoma Drainage Implants and Medium-sized 230-250 mm2 Implants. J Curr Glaucoma Pract 2017;11(1):8-15.

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Section: Discussionmentioning

confidence: 40%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Retrospective Comparison of Intermediate-term Efficacy of 350 mm2 Glaucoma Drainage Implants and Medium-sized 230—250 mm2 Implants

Meyer

Rodgers

Zou

et al. 2017

Journal of Current Glaucoma Practice

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Forniceal Conjunctival Pedicle Flap for the Treatment of Complex Glaucoma Drainage Device Tube Erosion

Grover

Merritt²,

Godfrey³

et al. 2013

JAMA Ophthalmol

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Comparative Cost-effectiveness of the Baerveldt Implant, Trabeculectomy With Mitomycin, and Medical Treatment

et al. 2015

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IMPORTANCEThe Tube vs Trabeculectomy Trial (TVT) found that the 350-mm 2 Baerveldt implant (tube) and trabeculectomy with mitomycin may be similarly effective in lowering intraocular pressure in primary open-angle glaucoma. However, to date, there are no published long-term clinical data on the cost-effectiveness of trabeculectomy with mitomycin vs tube insertion.OBJECTIVE To assess the cost-effectiveness of these procedures compared with maximal medical treatment. DESIGN, SETTING, AND PARTICIPANTSWe used the Markov cohort model with a 5-year time horizon to study a hypothetical cohort of 100 000 patients who required glaucoma surgery. MAIN OUTCOMES AND MEASURESQuality-adjusted life-years (QALYs) gained, costs from the societal perspective, and the incremental cost-effectiveness ratio of medical treatment, trabeculectomy, and tube insertion. Costs were identified from Medicare Current Procedural Terminology and Ambulatory Payment Classification reimbursement codes and Red Book medication costs. The QALYs were based on visual field and visual acuity outcomes. The hypothetical societal limit to resources was included using a willingness-to-pay threshold of $50 000 per QALY. Costs and utilities were discounted at 3% per year. Uncertainty was assessed using deterministic sensitivity analyses.

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The Ahmed Versus Baerveldt Study

Cited by 273 publications

References 31 publications

Retrospective Comparison of Intermediate-term Efficacy of 350 mm2 Glaucoma Drainage Implants and Medium-sized 230—250 mm2 Implants

Retrospective Comparison of Intermediate-term Efficacy of 350 mm2 Glaucoma Drainage Implants and Medium-sized 230—250 mm2 Implants

Forniceal Conjunctival Pedicle Flap for the Treatment of Complex Glaucoma Drainage Device Tube Erosion

Comparative Cost-effectiveness of the Baerveldt Implant, Trabeculectomy With Mitomycin, and Medical Treatment

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