The antidiabetic plants Tecoma stans (L.) Juss. ex Kunth (Bignoniaceae) and Teucrium cubense Jacq (Lamiaceae) induce the incorporation of glucose in insulin-sensitive and insulin-resistant murine and human adipocytes

Alonso-Castro, Ángel Josabad; Zapata-Bustos, Rocio; Romo-Yáñez, José; Camarillo-Ledesma, Paul; Gómez-Sánchez, Maricela; Salazar‐Olivo, Luis A.

doi:10.1016/j.jep.2009.09.060

Cited by 49 publications

(20 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Así, tenemos como ejemplo a la Jacaranda caucana, y Jacaranda mimosifolia, las cuales también han demostrado actividad antioxidante (19,20) ; también a la Tecoma stans, de la cual se ha demostrado efectos antidiabéticos a nivel de la inhibición de la enzima alfa-glucosidasa, así como el aumento de la captación de glucosa por la célula mediante el aumento de actividad de la insulina (21)(22)(23) .…”

Section: Discussionunclassified

Efecto hipoglicemiante de los extractos de tabebuia obscura (tahuari oscuro) sobre ratas con diabetes mellitus experimental

Aranda-Ventura¹,

Villacrés²,

Mego³

2016

Rev. per. med. integr.

View full text Add to dashboard Cite

Objetivo: Determinar el efecto del extracto acuoso liofilizado de Tabebuia obscura (Bureau & Schumann) Sandwith (TO) (tahuari oscuro) en los valores de glicemia en ratas con diabetes inducida experimentalmente. Materiales y Métodos: Se indujo diabetes experimental con aloxano a 24 ratas macho Holtzman los cuales fueron distribuidos en cuatro grupos de seis ratas cada uno. El grupo I recibió 3 mL de agua destilada (control), Grupo II: Glibenclamida 10 mg/kg (control positivo), Grupo III: Tabebuia obscura 100 mg/kg, Grupo IV: Tabebuia obscura 200 mg/kg. Se determinó la glicemia antes y después de la inducción con aloxano. Luego se evaluo a la 1h, 3h, 6h, 12h y 24h después de administrar las intervenciones. Resultados: Se encontraron diferencias significativas (p<0.05) en los promedios y se encontró correlación lineal en los valores de glicemia de los grupos II, III y IV. El grupo III y el grupo II tuvieron desempeños similares (p=0.456) en lograr disminuir la glicemia; con un coeficiente de correlación intraclase de 0.70. Conclusión: El extracto acuoso liofilizado de Tabebuia obscura en dosis de 100 mg/kg tiene un efecto hipoglicemiante similar a la Glibenclamida a 10 mg/kg en ratas Holtzman macho con diabetes experimental inducida por aloxano.

show abstract

Section: Discussionunclassified

Efecto hipoglicemiante de los extractos de tabebuia obscura (tahuari oscuro) sobre ratas con diabetes mellitus experimental

Aranda-Ventura¹,

Villacrés²,

Mego³

2016

Rev. per. med. integr.

View full text Add to dashboard Cite

show abstract

“…High density lipoprotein-cholesterol level improved [206] Kigelia africana (Lam.) Plant extract Reduction in blood glucose levels [207] Tabebuia rosea (Bertol) DC Plant extract Reduction of blood glucose levels [208] Tecoma stans Plant extract Intestinal alpha-glucosidase inhibition by decreasing the postprandial hyperglycaemia, reduced cholesterol and triglycerides levels [208] Plant extract Stimulating glucose uptake in both insulin-sensitive and insulin-resistant murine and human adipocytes without proadipogenic or antiadipogenic side effects [209] Eucommiaceae Eucommia ulmoides Oliv.…”

Section: Leaves Extractmentioning

confidence: 99%

A Review on Role of Plant(s) Extracts and its Phytochemicals for the Management of Diabetes

2015

J Diabetes Metab

View full text Add to dashboard Cite

The present review focused on plant extracts or phytochemicals role in diabetes management has been tried by many researchers. I have attempted to compile a list of total 419 plant species belongs to 133 families have been used for in-vitro and in-vivo studies. The plant extract or phytochemicals have involved in decreasing or increasing or stimulating different mechanisms in reducing diabetes and they have been listed in tabular form. By this review, few molecules are used in diabetes management and they possess molecular mechanisms or involved in signal transduction to initiate the insulin production or utilization of blood glucose level bring down to normal stage. The researchers have used different parts of the plant extracts or individual phytochemicalsfor antidiabetic activities. This review brings the researcher data on antidiabetic activities of different plant extracts role in reducing of diabetic problems.

show abstract

“…Many traditional medicines in use are derived from medicinal plants, minerals and organic matter [2]. Botanicals are less expensive and easily available because of their natural occurrence in abundance (Opara and Wokocha, 2008 [3].One species, T.stans have been known to posses anti diabetic activity and the compounds like tecomine and tecostanin have been isolated from it [4][5][6][7][8]. Based on such literatures, the cytotoxic potential of one of the members of Bignoniaceae, Tecoma castanifolia (D. Don) Melch was analysed in this study.…”

Section: Global Cancer Facts and Figures 3rd Edition) Current Estimatementioning

confidence: 99%

Cytotoxicity Analysis of Crude Leaf Extracts from Tecoma castanifolia (D. Don) Melch on Brine Shrimp and MCF-7 Cell Line

2015

IJSR

View full text Add to dashboard Cite

Abstract:To assess the possibility of cytotoxic potential of T.castanifolia leaf extract. Since this family of plants have effective cytotoxic potential against cancer, analysis of this particular species was carried out. The acetone, ethylacetate and ethanol extracts were subjected to brine shrimp lethality assay and cytotoxicity analysis against MCF-7 cell line. MTT assay of these three extracts showed the ethyl acetate extract to be most effectively cytotoxic. Further studies can be carried out in this aspect to bring out the complete effectiveness of the extract and compounds therein.

show abstract

The antidiabetic plants Tecoma stans (L.) Juss. ex Kunth (Bignoniaceae) and Teucrium cubense Jacq (Lamiaceae) induce the incorporation of glucose in insulin-sensitive and insulin-resistant murine and human adipocytes

Cited by 49 publications

References 37 publications

Efecto hipoglicemiante de los extractos de tabebuia obscura (tahuari oscuro) sobre ratas con diabetes mellitus experimental

Efecto hipoglicemiante de los extractos de tabebuia obscura (tahuari oscuro) sobre ratas con diabetes mellitus experimental

A Review on Role of Plant(s) Extracts and its Phytochemicals for the Management of Diabetes

Cytotoxicity Analysis of Crude Leaf Extracts from Tecoma castanifolia (D. Don) Melch on Brine Shrimp and MCF-7 Cell Line

Contact Info

Product

Resources

About