2024
DOI: 10.1002/efd2.70005
|View full text |Cite
|
Sign up to set email alerts
|

The antihyperuricemic and nephroprotective effect of puerarin by reducing uric acid level and exerting anti‐inflammatory activity

Muxuan Wang,
Yong Zhao,
Nan Chen
et al.

Abstract: Hyperuricemia (HUA) is a common metabolic disease and kidney injury is one of its main complications. As a typical natural flavonoid, puerarin (PEA) has a range of pharmacological activity but the antihyperuricemic mechanism of PEA has not been reported. Herein, the inhibitory activity of PEA against xanthine oxidase (XOD) was evaluated by in vitro enzymatic reaction, and kinetic analysis, the antihyperuricemic activity, and nephroprotective effect of PEA were studied in HUA mice. The enzymatic reaction showed… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 46 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?