The application value of couch height-based positioning in postoperative adjuvant radiotherapy for breast cancer

Abstract

The purpose of this study is to explore the application value of positioning based on the treatment couch height in radiotherapy for left-sided breast cancer. Sixty patients who had undergone radical mastectomy for left breast cancer were selected, with each patient undergoing positioning based on the treatment couch height (couch height group) and positioning based on the reference marking lines (reference line group), to obtain the corresponding positioning errors. Meanwhile, 20 of 60 patients were randomly selected, and the planning system was used to simulate the changes in radiation doses in planning target volume (PTV) and organs at risk (OAR) along with the changes in positioning errors in dorsal (increasing couch height) and ventral (decreasing couch height), respectively. Compared with the original plan, when the positioning error in the dorsal direction reached 3mm, Dmean, V30, and V20 in The ipsilateral lung were increased by 35.12%, 16.35%, and 10.6% respectively, and V50 in PTV was decreased by 0.99% (all p < 0.05); when the positioning error in the ventral direction reached 1.5 mm, V50, V48, and V45 were decreased by 2.07%, 0.58%, and 0.14% respectively. The homogeneity index (HI) was increased by 14.28% (all p < 0.05). There was a statistically significant difference in the positioning errors in the ventral-dorsal directions between the couch height group (0.16±0.14 cm) and reference line group (0.36±0.25 cm) (p < 0.05); the percentages of the absolute positioning errors within 1.5mm and 3mm were 52.4%, 88.7% respectively in the couch height group and 29.8%, 54.4% respectively in the reference line group, (all p < 0.05). Dorsal positioning errors greater than 3 mm significantly worsen the dose distribution for both the PTV and OAR, while positioning based on the treatment couch height keeps 88.7% of positioning errors within 3 mm; ventral positioning errors greater than 1.5 mm result in significant changes in the dose within the PTV. Compared to the reference line group, positioning based on the treatment couch height controls 52.4% of positioning errors within 1.5 mm. Therefore, couch height positioning demonstrates greater advantages in managing ventral-dorsal positioning errors. This study provides a reference for clinical positioning in postoperative adjuvant radiotherapy of breast cancer. Keywords: Breast cancer radiotherapy, Positioning error, Treatment couch height, Dose distribution