INTRODUCTION: The association between oral health and vascular disease has been recently studied and it can be seen that periodontal disease can influence health at all. On the other hand, atherosclerosis is a progressive disease with accumulation of fibrotic and inflammatory elements resulting in endothelial lesions, and increase of incidence when associated to chronic inflammations. It is known the association between Porphyromonas gingivalis and heart diseases, as this microorganism has been found in atheroma plaques, as other periodontal pathogens.OBJECTIVE: Search information in literature that confirms the relationship between periodontal disease and hyperlipidemia associated to vascular disease.METHODS: For this article revision, an online search has been made in scientific libraries such as the Virtual Library in Health (BVS, Bireme); PubMed; Digital Brazilian Theses and Dissertations (BDTD) from 2000 to 2014, using as key words periodontal disease, vascular disease, hyperlipidemia.CONCLUSION: It has been confirmed by some authors the relation between periodontal disease and hyperlipidemia, otherwise, some contradictory results due to risk factors such as age, food intake and social and cultural factors. Mechanisms in which these factors acts in this progression still have not been clear.