The association between plasma caspase-3, atherosclerosis, and vascular function in the Dallas Heart Study

Abstract

Caspase-3 independently associates with CAC, AWT, and AC, suggesting a link between apoptosis and atherosclerosis.

Soluble ST2 Is Associated with All-Cause and Cardiovascular Mortality in a Population-Based Cohort: The Dallas Heart Study

“…The following analytes were measured previously and the methods have been described: growth differentiation factor 15 (GDF-15) (16 ), cystatin C (17 ), highsensitivity C-reactive protein (hsCRP) (19 ), pulmonary surfactant protein B (SP-B) (20 ), osteoprotegerin (21 ), N-terminal pro-B-type natriuretic peptide (NTproBNP) (22 ), cardiac troponin T (cTnT) measured with a highly sensitive assay (23 ), tumor necrosis factor-␣1 receptor (TNFR1A) (20 ), lymphotoxin ␤ receptor (LTBR) (24 ), soluble vascular cell adhesion molecule 1 (sVCAM-1) (25 ), soluble intercellular adhesion molecule 1 (sICAM-1) (25 ), soluble receptor for advanced glycation end products (26 ), caspase-3 (18 ), fructosamine (22 ), adiponectin (27 ), monocyte chemoattractant protein 1 (MCP-1) (28 ), homeostasis model assessment-insulin resistance (25 ), and IL-18 (29 ).…”

Sarcopenia: Clinical evaluation, biological markers and other evaluation tools

“…Because these markers have little specificity for skeletal muscle and strength loss, they may have limited utility for the assessment of sarcopenia. The measurement of circulating ubiquitin proteasome 57-59 and plasma caspase 60 may be more specific markers of muscle protein breakdown, however, to our knowledge these circulating markers have not been studied in association with age-related sarcopenia.…”

Clinical Characteristics, Vascular Function, and Inflammation in Women With Angina in the Absence of Coronary Atherosclerosis

“…Cardiac magnetic resonance was performed on the same scanner using a body coil with electrocardiography gating. Aortic crosssectional area was then measured on the axial images at the level of the pulmonary bifurcation using the QFLOW software package (version 4.1.6, Medis Medical Imaging Systems, Leiden, the Netherlands), and aortic slice volume was calculated as the aortic cross-sectional area multiplied by the aortic slice thickness as previously described (10). Arm blood pressure measurements were obtained at the time of the scan using an automated WelchAllyn sphygmomanometer, and pulse pressure was then calculated as systolic blood pressure minus diastolic blood pressure.…”