The Association Between Substance Use Disorder and Depression During the COVID-19 Lockdown in Spain and the Moderating Role of Social Support: a Cross-Sectional Study

Faris, Lydia Hanaa; Gabarrell‐Pascuet, Aina; Félez-Nóbrega, Mireia; Cristóbal-Narváez, Paula; Vilagut, Gemma; Olaya, Beatriz; Alonso, Jordi; Haro, Josep María; López-Carrilero, Raquel; Domènech‐Abella, Joan

doi:10.1007/s11469-021-00651-7

Cited by 12 publications

(9 citation statements)

References 27 publications

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“…As regards the statistical analysis conducted, thirty-six surveys developed a multivariate model, the most frequent being binary logistic (16), linear (eight surveys) and mixed (six surveys). Other multivariate models used were multi-level (73), cluster (44), principal components (32), random forest (28) and structural equations (6).…”

Section: Resultsmentioning

confidence: 99%

Scoping review of the methodology of large health surveys conducted in Spain early on in the COVID-19 pandemic

Garrido

Conde

Rueda

et al. 2023

Front. Public Health

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BackgroundThe use of health surveys has been key in the scientific community to promptly communicate results about the health impact of COVID-19. But what information was collected, where, when and how, and who was the study population?ObjectiveTo describe the methodological characteristics used in large health surveys conducted in Spain early on in the COVID-19 pandemic.MethodsScoping review. Inclusion criteria: observational studies published between January 2020 and December 2021, with sample sizes of over 2,000 persons resident in Spain. Databases consulted: PubMed, CINAHL, Literatura Latinoamericana y del Caribe en CC de la Salud, Scopus, PsycINFO, Embase, Sociological Abstracts, Dialnet and Web of Science Core Collection. We analyzed the characteristics of the literature references, methodologies and information gathered in the surveys selected. Fifty five studies were included.ResultsSixty percentage of the studies included had mental health as their main topic and 75% were conducted on the general adult population. Thirteen percentage had a longitudinal design, 93% used the internet to gather information and the same percentage used non-probability sampling. Thirty percentage made some type of sampling correction to reduce coverage or non-response biases, but not selection biases. Sixty seven percentage did not state the availability of their data.ConclusionsConsistent with the extensive use of non-probability sampling without any bias correction in the extraordinary setting created by COVID-19, quality population frameworks are required so that probability and representative samples can be extracted quickly to promptly address other health crises, as well as to reduce potential coverage, non-response and particularly selection biases by utilizing reweighting techniques. The low data accessibility despite the huge opportunity that COVID-19 provided for Open Science-based research is striking.

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Section: Resultsmentioning

confidence: 99%

Scoping review of the methodology of large health surveys conducted in Spain early on in the COVID-19 pandemic

Garrido

Conde

Rueda

et al. 2023

Front. Public Health

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“…En este primer estado de alarma analizado en nuestro estudio, destaca que los pacientes presentaban menor edad media. Otros estudios así lo reportan (Faris et al, 2021) y es que el confinamiento parece haber afectado en particular a los adultos más jóvenes, probablemente porque su bienestar psicosocial depende de interacciones sociales frecuentes en mayor medida que en el caso de los adultos mayores (Carstensen, 1992).…”

Section: Discussionunclassified

Atenciones urgentes realizadas durante la pandemia por consumo de tóxicos en una provincia española

Irigoyen-Otiñano¹,

Ibarra-Pertusa²,

Nicolau-Subires³

et al. 2023

Adicciones

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During periods of isolation, people with substance use disorders may reduce tension, stress, uncertainty and possible distress by increasing the use of substances or practices that they have abused. The objective of this study was to evaluate the impact of the pandemic on emergency care and continuity of care for patients with substance use disorders. Method: Study carried out in the only psychiatric emergency service in the province at the Hospital Universitario Santa María de Lérida, which cares for 431,183 people. Sociodemographic, clinical and evolutionary variables were collected from all the patients treated during a period prior to lockdown (January 13, 2020, until March 14, 2020) and during the first (March 15, 2020 until June 20, 2020) and second states of emergency (from October 25, 2020 to May 9, 2021). Results: 908 patients attended with substance use disorder, representing 23.8% of all visits. During the first state of emergency, visits increased (p < 0.001) with a decrease in the average age (p = 0.0023). During the second state of emergency, there was an increase in the use of alcohol with respect to the rest of toxic substances (p < 0.001) and an increase in the visits of patients without prior followup (p = 0.005). Conclusions: Substance use disorder consultations increased in the first state of emergency, with patients being younger and attending for reasons related to outpatient discontinuity, while in the second state of emergency, alcohol use increased in people without prior follow-up and with small social networks. Admissions in the first state of emergency were shorter, with no subsequent link to other detoxification treatment centers and with an earlier return to the emergency room, especially in female users.

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“…2 The data were analyzed with the Wilcoxon signed-rank test; the effect size is expressed as the rank correlation coefficient (r c ). 3 The data were analyzed with the T-test for independent variables; the effect size is expressed as Cohen's d. 4 The data were analyzed with the Mann-Whitney U-test; the effect size is expressed as Glass's rank-biserial correlation coefficient (r g ). confidence interval (box), 95% CI + one standard deviation (whisker), and raw data.…”

Section: Correlations Between the Depression Scales And Inflammatory ...mentioning

confidence: 99%

Bovine colostrum supplementation as a new perspective in depression and substance use disorder treatment: a randomized placebo-controlled study

Durkalec-Michalski,

Główka,

Podgórski

et al. 2024

Front. Psychiatry

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IntroductionThis randomized, placebo-controlled, double-blind, parallel study aimed to evaluate the effect of 3-month supplementation of bovine colostrum (BOV-COL; 8x400 mg per day) on the outcomes of depression treatment in hospitalized patients with substance use disorder (SUD). The hypothesis is that BOV-COL supplementation as an add-on treatment results in favorable alternations in selected blood inflammatory markers or neurotransmitters, leading to better depression treatment outcomes compared with placebo (PLA).MethodsPatients with a Minnesota Multiphasic Personality Inventory-2 score ≥60 points were enrolled. Twenty-nine participants (n=18 in the BOV-COL group and n=11 in the PLA group) completed the protocol.ResultsThe mean Beck Depression Inventory-II score was significantly reduced after supplementation in both groups. However, the mean 17-point Hamilton Depression Rating Scale score was decreased in the BOV-COL group, but not in the PLA group. In the BOV-COL group, there was a reduction in interleukin (IL)-1, IL-6, IL-10, the IL-6:IL-10 ratio, IL-17, and tumor necrosis factor alpha (TNF-α), while in the PLA group only IL-6 decreased. Favorable alternations in the total count and differentials of white blood cell subsets were more pronounced in the BOV-COL. There were no changes in neurotransmitter concentrations.ConclusionsBOV-COL supplementation is a promising add-on therapy in patients with depression and SUD.

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The Association Between Substance Use Disorder and Depression During the COVID-19 Lockdown in Spain and the Moderating Role of Social Support: a Cross-Sectional Study

Cited by 12 publications

References 27 publications

Scoping review of the methodology of large health surveys conducted in Spain early on in the COVID-19 pandemic

Scoping review of the methodology of large health surveys conducted in Spain early on in the COVID-19 pandemic

Atenciones urgentes realizadas durante la pandemia por consumo de tóxicos en una provincia española

Bovine colostrum supplementation as a new perspective in depression and substance use disorder treatment: a randomized placebo-controlled study

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